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Invitrogen

JNK2 Polyclonal Antibody

View all (41) JNK2 antibodies

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JNK2 Polyclonal Antibody

Product Details

PA5-102407

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human MAPK9(Accession P45984), corresponding to amino acid residues M1-Y11.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2851812

Product Specific Information

Antibody detects endogenous levels of total JNK2.

Target Information

MAPK9 (JNK2) is a serine/threonine kinase which plays an important role in the MAPK pathway. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: c-Jun kinase 2; c-Jun N-terminal kinase 2; JNK; JNK-46; JNK-55; JNK/SAPK alpha; JNK1; JNK1A2; JNK21B1/2; Jun kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAPK 10; MAPK 9; MAPK10; MAPK8; MAPK9; mitogen activated protein kinase 9; Mitogen-activated protein kinase 9; OTTHUMP00000161542; OTTHUMP00000161543; p54-alpha; PRKM8; protein kinase, mitogen-activated 9; SAPK-alpha; SAPK1; SAPK1a; SAPK1c; stress activated protein kinase alpha II; Stress-activated protein kinase 1a; Stress-activated protein kinase JNK2; unnamed protein product

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Gene Aliases: AI851083; JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; MAPK9; p54a; p54aSAPK; PRKM9; SAPK; SAPK1A

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UniProt ID: (Human) P45984, (Rat) P49186, (Mouse) Q9WTU6

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Entrez Gene ID: (Human) 5601, (Rat) 50658, (Mouse) 26420

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Function(s)
nucleotide binding protein kinase activity protein serine/threonine kinase activity JUN kinase activity MAP kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding kinase activity transferase activity protein serine kinase activity transcription factor binding cysteine-type endopeptidase activator activity involved in apoptotic process mitogen-activated protein kinase kinase kinase binding transferase activity, transferring phosphorus-containing groups non-receptor serine/threonine protein kinase
Process(es)
MAPK cascade protein phosphorylation JNK cascade positive regulation of gene expression positive regulation of macrophage derived foam cell differentiation positive regulation of protein ubiquitination positive regulation of proteasomal ubiquitin-dependent protein catabolic process cellular response to reactive oxygen species Fc-epsilon receptor signaling pathway regulation of circadian rhythm regulation of mRNA stability response to cadmium ion rhythmic process modulation of synaptic transmission mRNA destabilization protein localization to tricellular tight junction positive regulation of podosome assembly cellular senescence inflammatory response to wounding apoptotic signaling pathway positive regulation of cytokine production involved in inflammatory response positive regulation of apoptotic signaling pathway release of cytochrome c from mitochondria positive regulation of protein phosphorylation protein targeting to mitochondrion activation of cysteine-type endopeptidase activity involved in apoptotic process JUN phosphorylation central nervous system development response to mechanical stimulus response to toxic substance response to organic substance positive regulation of cell morphogenesis involved in differentiation response to amine neuron projection development positive regulation of prostaglandin biosynthetic process regulation of protein ubiquitination positive regulation of prostaglandin secretion positive regulation of chemokine production cellular response to UV response to drug positive regulation of apoptotic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of nitric oxide biosynthetic process positive regulation of transcription, DNA-templated regulation of JNK cascade positive regulation of nitric-oxide synthase biosynthetic process cellular response to lipopolysaccharide cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to growth factor stimulus phosphorylation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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