In Western blots, approximately 35% cross-reactivity with recombinant human Jagged 1 is observed and less than 1% cross-reactivity with recombinant rat Jagged 1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.
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Protein Aliases: Jagged2; Protein jagged-2
Gene Aliases: HJ2; JAG2; SER2
UniProt ID: (Human) Q9Y219
Entrez Gene ID: (Human) 3714