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Invitrogen
JunB Polyclonal Antibody
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Product Details
PA5-17263
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues surrounding Gly53 of human JunB
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: activator protein 1; Jun B; jun B proto-oncogene; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; Transcription factor JunB
Gene Aliases: AP-1; JUNB
UniProt ID: (Human) P17275
Entrez Gene ID: (Human) 3726
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
transcription factor binding
basic leucine zipper transcription factor
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
osteoblast differentiation
trophectodermal cell differentiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to radiation
response to light stimulus
response to mechanical stimulus
regulation of cell death
osteoclast differentiation
response to lipopolysaccharide
response to progesterone
cellular response to hormone stimulus
osteoblast proliferation
response to cytokine
regulation of cell proliferation
response to drug
response to peptide hormone
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
decidualization
response to corticosterone
response to cAMP
regulation of cell cycle
embryonic process involved in female pregnancy
labyrinthine layer blood vessel development
cellular response to calcium ion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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