Recommended positive controls: HepG2, HCT116.
Predicted reactivity: Mouse (86%), Rat (84%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: katanin p60 (ATPase containing) subunit A 1; katanin p60 (ATPase-containing) subunit A 1; Katanin p60 ATPase-containing subunit A1; Katanin p60 subunit A1; KATNA1; p60 katanin
Gene Aliases: KATNA1
UniProt ID: (Human) O75449
Entrez Gene ID: (Human) 11104