Positive Control: SK-N-SH, mouse hippocampus, rat hippocampus, rat spinal cord
Predicted Reactivity: Mouse (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Electroneutral potassium-chloride cotransporter 2; erythroid K-Cl cotransporter 2; Furosemide-sensitive K-Cl cotransporter; hKCC2; K-Cl cotransporter 2; KCC2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; member 5; mKCC2; mKIAA1176; Neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; Slc12a5; solute carrier family 12; solute carrier family 12 (potassium/chloride transporter), member 5; Solute carrier family 12 member 5; solute carrier family 12, member 5
Gene Aliases: EIEE34; EIG14; hKCC2; KCC2; KIAA1176; mKIAA1176; SLC12A5