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KCC4 Antibody (A304-442A) in WB
Detection of human KCC4 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) prepared using NETN buffer from Jurkat cells. Antibodies: Affinity purified rabbit anti-KCC4 antibody A304-442A (lot A304-442A-1) used for IP at 6 µg per reaction. KCC4 was also immunoprecipitated by rabbit anti-KCC4 antibody A304-443A. For blotting immunoprecipitated KCC4, A304-442A was used at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A304-442A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Between 1 and 50
Conjugate
Unconjugated
Form
liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Electroneutral potassium-chloride cotransporter 4; K-Cl cotransporter 4; potassium/chloride transporter KCC4; solute carrier family 12 (potassium/chloride transporter), member 7; solute carrier family 12 (potassium/chloride transporters), member 7; Solute carrier family 12 member 7
Gene Aliases: KCC4; SLC12A7
UniProt ID: (Human) Q9Y666
Entrez Gene ID: (Human) 10723
Molecular Function:
secondary carrier transporter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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