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KCNAB1 Polyclonal Antibody

View all (8) KVbeta1 (KCNAB1) antibodies

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KCNAB1 Polyclonal Antibody

Product Details

14697-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2400
-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:20-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KCNAB1 Fusion Protein Ag6339 (82-401 aa encoded by BC043166)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Amount

52.5 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: RVSCLGLGT WVTFGGQISD EVAERLMTIA YESGVNLFDT AEVYAAGKAE VILGSIIKKK GWRRSSLVIT TKLYWGGKAE TERGLSRKHI IEGLKGSLQR LQLEYVDVVF ANRPDSNTPM EEIVRAMTHV INQGMAMYWG TSRWSAMEIM EAYSVARQFN MIPPVCEQAE YHLFQREKVE VQLPELYHKI GVGAMTWSPL ACGIISGKYG NGVPESSRAS LKCYQWLKER IVSEEGRKQQ NKLKDLSPIA ERLGCTLPQL AVAWCLRNEG VSSVLLGSST PEQLIENLGA IQVLPKMTSH VVNEIDNILR NKPYSKKDYR S (82-401 aa encoded by BC043166)

Target Information

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNAB1 gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: alternative splice product of the Shaker beta 1 gene, see GenBank Accession Numbers U16953 and L39833; K(+) channel subunit beta-1; K+ channel Beta1a chain; Kv-beta-1; potassium channel beta 3 chain; potassium channel beta3 subunit; potassium channel shaker chain beta 1a; potassium channel, voltage gated subfamily A regulatory beta subunit 1; potassium voltage gated channel shaker related subfamily beta member 1; potassium voltage gated channel, shaker related subfamily, beta member 1; potassium voltage-gated channel subfamily A member regulatory beta subunit 1; potassium voltage-gated channel, shaker-related subfamily, beta member 1; shaker-related subfamily member 1; unnamed protein product; voltage-gated potassium channel beta subunit; Voltage-gated potassium channel subunit beta-1

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Gene Aliases: AKR6A3; Akr8a8; hKvb3; hKvBeta3; KCNA1B; KCNAB1; KV-BETA-1; Kvb1; Kvb1.3; Kvbeta1.1; KvBeta3; mKv(beta)1

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UniProt ID: (Human) Q14722, (Mouse) P63143, (Rat) P63144

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Entrez Gene ID: (Human) 7881, (Mouse) 16497, (Rat) 29737

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Function(s)
carbonyl reductase (NADPH) activity voltage-gated potassium channel activity protein binding alcohol dehydrogenase (NADP+) activity potassium channel regulator activity oxidoreductase activity protein domain specific binding ion channel binding NADPH binding molecular function inhibitor activity C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity aldo-keto reductase (NADP) activity isocitrate dehydrogenase activity mevaldate reductase activity voltage-gated ion channel activity gluconate dehydrogenase activity steroid dehydrogenase activity epoxide dehydrogenase activity 5-exo-hydroxycamphor dehydrogenase activity 2-hydroxytetrahydrofuran dehydrogenase activity acetoin dehydrogenase activity phenylcoumaran benzylic ether reductase activity D-xylose:NADP reductase activity L-arabinose:NADP reductase activity D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid dehydrogenase activity, acting on the CH-CH group of donors (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity 3-hydroxymenthone dehydrogenase activity very long-chain-3-hydroxyacyl-CoA dehydrogenase activity dihydrotestosterone 17-beta-dehydrogenase activity (R)-2-hydroxyisocaproate dehydrogenase activity L-arabinose 1-dehydrogenase (NADP+) activity L-xylulose reductase (NAD+) activity 3-ketoglucose-reductase activity (R)-2-hydroxyglutarate dehydrogenase activity D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity
Process(es)
ion transport potassium ion transport learning or memory transmembrane transport potassium ion transmembrane transport regulation of potassium ion transmembrane transport regulation of delayed rectifier potassium channel activity negative regulation of voltage-gated potassium channel activity transport regulation of ion transmembrane transport oxidation-reduction process regulation of potassium ion transmembrane transporter activity negative regulation of delayed rectifier potassium channel activity
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