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Product Details
19963-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Published species |
Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Peptide |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.56 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
The antibody is specific to KCNB1.
Target Information
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Delayed rectifier potassium channel 1; DRK1; KCB1; mShab; Potassium voltage-gated channel subfamily B member 1; potassium voltage-gated channel, Shab-related subfamily, member 1; Voltage-gated potassium channel subunit Kv2.1
Gene Aliases: DRK1; KCNB1; Kcr1-1; Kv2.1; Shab
UniProt ID: (Human) Q14721, (Mouse) Q03717
Entrez Gene ID: (Human) 3745, (Mouse) 16500
Molecular Function:
voltage-gated ion channel
action potential
vesicle docking involved in exocytosis
glutamate receptor signaling pathway
positive regulation of norepinephrine secretion
cellular response to nutrient levels
positive regulation of catecholamine secretion
regulation of ion transmembrane transport
glucose homeostasis
positive regulation of calcium ion-dependent exocytosis
negative regulation of insulin secretion
regulation of insulin secretion
protein homooligomerization
cellular response to glucose stimulus
potassium ion transmembrane transport
protein targeting to plasma membrane
positive regulation of protein targeting to membrane
regulation of action potential
positive regulation of long term synaptic depression
regulation of motor neuron apoptotic process
transport
ion transport
potassium ion transport
protein oligomerization
transmembrane transport
delayed rectifier potassium channel activity
protein binding
ubiquitin-like protein binding
ion channel binding
protein heterodimerization activity
SNARE binding
ion channel activity
voltage-gated ion channel activity
voltage-gated potassium channel activity
potassium channel activity
outward rectifier potassium channel activity
protein N-terminus binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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