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Product Details
PA5-56233
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KCNE2. Recombinant protein control fragment (Product #RP-102558).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642920
Product Specific Information
Immunogen sequence: MSTLSNFTQT LEDVFRRIFI TYMDNWRQNT TAEQEALQAK VDAE
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 75%.
Target Information
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac voltage-gated potassium channel accessory subunit 2; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2; Minimum potassium ion channel-related peptide 1; MinK-related peptide 1; minK-related peptide-1; MiRP1; Potassium channel subunit beta MiRP1; potassium channel subunit, MiRP1; potassium channel, voltage gated subfamily E regulatory beta subunit 2; Potassium voltage-gated channel subfamily E member 2; potassium voltage-gated channel, Isk-related family, member 2; voltage-gated K+ channel subunit MIRP1
Gene Aliases: ATFB4; KCNE2; LQT5; LQT6; MIRP1
UniProt ID: (Human) Q9Y6J6
Entrez Gene ID: (Human) 9992
inward rectifier potassium channel activity
delayed rectifier potassium channel activity
protein binding
potassium channel regulator activity
protein homodimerization activity
ion channel binding
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
voltage-gated ion channel
aging
potassium ion import
cellular response to drug
tongue development
regulation of membrane repolarization
regulation of ventricular cardiac muscle cell membrane repolarization
cardiac conduction
potassium ion export
potassium ion transmembrane transport
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
membrane repolarization
membrane repolarization during action potential
regulation of heart rate by cardiac conduction
membrane repolarization during ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transport
positive regulation of voltage-gated calcium channel activity
positive regulation of proteasomal protein catabolic process
regulation of inward rectifier potassium channel activity
regulation of cyclic nucleotide-gated ion channel activity
regulation of delayed rectifier potassium channel activity
negative regulation of delayed rectifier potassium channel activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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