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Invitrogen
KCNE3 Polyclonal Antibody
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Product Details
PA5-33865
Product Specifications
Species Reactivity
Bat,
Bovine,
Dog,
Chicken,
Horse,
Hamster,
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 14 amino acid peptide from internal region of human KCNE3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac voltage-gated potassium channel accessory subunit; Minimum potassium ion channel-related peptide 2; MinK-related peptide 2; MiRP2; Potassium channel subunit beta MiRP2; potassium channel, voltage gated subfamily E regulatory beta subunit 3; Potassium voltage-gated channel subfamily E member 3; potassium voltage-gated channel, Isk-related family, member 3; potassium voltage-gated channel, Isk-related subfamily, gene 3; potassium voltage-gated channel, Isk-related subfamily, member 3; voltage-gated K+ channel subunit MIRP2
Gene Aliases: 2210017H05Rik; HOKPP; HYPP; KCNE3; MiRP2
UniProt ID: (Human) Q9Y6H6, (Rat) Q9JJV7, (Mouse) Q9WTW2
regulation of membrane repolarization
potassium ion transmembrane transport
positive regulation of voltage-gated calcium channel activity
negative regulation of delayed rectifier potassium channel activity
regulation of potassium ion transport
regulation of potassium ion transmembrane transport
negative regulation of voltage-gated potassium channel activity
transport
ion transport
potassium ion transport
regulation of ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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