Proteintech

KCNJ15 Polyclonal Antibody

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KCNJ15 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver using 15988-1-AP (KCNJ15 antibody) at dilution of 1:100 (under 40x lens).

KCNJ15 Antibody in Western Blot (WB) — HepG2 cells were subjected to SDS PAGE followed by western blot with 15988-1-AP (KCNJ15 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

KCNJ15 Antibody in Immunoprecipitation (IP) — IP result of anti-KCNJ15 (IP:15988-1-AP, 4ug; Detection:15988-1-AP 1:500) with HepG2 cells lysate 1000ug.

Product Details

15988-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KCNJ15 Fusion Protein Ag8795 (94-375 aa encoded by BC013327)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

Immunogen sequence: DLEPGEPIS NHTPCIMKVD SLTGAFLFSL ESQTTIGYGV RSITEECPHA IFLLVAQLVI TTLIEIFITG TFLAKIARPK KRAETIKFSH CAVITKQNGK LCLVIQVANM RKSLLIQCQL SGKLLQTHVT KEGERILLNQ ATVKFHVDSS SESPFLILPM TFYHVLDETS PLRDLTPQNL KEKEFELVVL LNATVESTSA VCQSRTSYIP EEIYWGFEFV PVVSLSKNGK YVADFSQFEQ IRKSPDCTFY CADSEKQQLE EKYRQEDQRE RELRTLLLQQ SNV (94-375 aa encoded by BC013327)

Target Information

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

KCNJ15 Expression and Malignant Behavior of Esophageal Squamous Cell Carcinoma.

Annals of surgical oncology

Nakamura S,Kanda M,Koike M,Shimizu D,Umeda S,Hattori N,Hayashi M,Tanaka C,Kobayashi D,Yamada S,Omae K,Kodera Y

Wed Jul 01 00:00:00 EDT 2020

KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis.

Nature communications

Nakajima KI,Zhu K,Sun YH,Hegyi B,Zeng Q,Murphy CJ,Small JV,Chen-Izu Y,Izumiya Y,Penninger JM,Zhao M

Fri Oct 09 00:00:00 EDT 2015

KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis.

Nature communications

Nakajima KI,Zhu K,Sun YH,Hegyi B,Zeng Q,Murphy CJ,Small JV,Chen-Izu Y,Izumiya Y,Penninger JM,Zhao M

Fri Oct 09 00:00:00 EDT 2015

KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis.

Nature communications

Nakajima KI,Zhu K,Sun YH,Hegyi B,Zeng Q,Murphy CJ,Small JV,Chen-Izu Y,Izumiya Y,Penninger JM,Zhao M

Fri Oct 09 00:00:00 EDT 2015

KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis.

Nature communications

Nakajima KI,Zhu K,Sun YH,Hegyi B,Zeng Q,Murphy CJ,Small JV,Chen-Izu Y,Izumiya Y,Penninger JM,Zhao M

Fri Oct 09 00:00:00 EDT 2015

Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations.

DNA research : an international journal for rapid publication of reports on genes and genomes

Kobayashi A,Donaldson DS,Kanaya T,Fukuda S,Baillie JK,Freeman TC,Ohno H,Williams IR,Mabbott NA

Mon Oct 01 00:00:00 EDT 2012

Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations.

DNA research : an international journal for rapid publication of reports on genes and genomes

Kobayashi A,Donaldson DS,Kanaya T,Fukuda S,Baillie JK,Freeman TC,Ohno H,Williams IR,Mabbott NA

Mon Oct 01 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: ATP-sensitive inward rectifier potassium channel 15; Inward rectifier K(+) channel Kir1.3; Inward rectifier K(+) channel Kir4.2; inward rectifier K+ channel KIR4.2; Potassium channel, inwardly rectifying subfamily J member 15; potassium channel, inwardly rectifying subfamily J, member 15; potassium inwardly-rectifying channel, subfamily J, member 15

Gene Aliases: 4930414N08Rik; AI182284; AI267127; IRKK; KCNJ14; KCNJ15; KIR1.3; KIR4.2

UniProt ID: (Human) Q99712, (Rat) Q91ZF1, (Mouse) O88932

Entrez Gene ID: (Human) 3772, (Rat) 170847, (Mouse) 16516

Molecular Function: ion channel transporter