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Proteintech
KCNK4 Polyclonal Antibody
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Product Details
27113-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KCNK4 Fusion Protein Ag25931 (261-393 aa encoded by BC033577)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SRRTRAEMG GLTAQAASWT GTVTARVTQR AGPAAPPPEK EQPLLPPPPC PAQPLGRPRS PSPPEKAQPP SPPTASALDY PSENLAFIDE SSDTQSERGC PLPRAPRGRR RPNPPRKPVR PRGPGRPRDK GVPV (261-393 aa encoded by B C033577)
Target Information
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: K2P4.1; K2P4.1 potassium channel; KT4.1b; leak channel; Potassium channel subfamily K member 4; potassium channel, subfamily K, member 4; potassium channel, two pore domain subfamily K, member 4; potassium inwardly-rectifying channel subfamily K member 4; potassium inwardly-rectifying channel, subfamily K, member 4; protein expressed in male leptotene and zygotene spermatocytes 622; TRAAK; TWIK-related arachidonic acid-stimulated potassium channel protein; two pore K(+) channel KT4.1; two pore K+ channel KT4.1; Two pore potassium channel KT4.1; unnamed protein product
Gene Aliases: FHEIG; K2p4.1; KCNK4; KT4.1; MLZ-622; Tex40; TRAAK; TRAAK1; TRAAKt
UniProt ID: (Human) Q9NYG8, (Mouse) O88454, (Rat) G3V8V5
Entrez Gene ID: (Human) 50801, (Mouse) 16528, (Rat) 116489
potassium channel activity
protein binding
outward rectifier potassium channel activity
potassium ion leak channel activity
identical protein binding
metal ion binding
temperature-gated cation channel activity
mechanically-gated potassium channel activity
voltage-gated ion channel activity
ion channel
transporter
ion transport
potassium ion transport
memory
response to mechanical stimulus
neuronal action potential
sensory perception of pain
ion transmembrane transport
sensory perception of temperature stimulus
detection of mechanical stimulus involved in sensory perception of touch
cellular response to mechanical stimulus
cellular response to fatty acid
cellular response to acidic pH
cellular response to alkaline pH
cellular response to temperature stimulus
potassium ion transmembrane transport
cellular response to arachidonate
response to ultrasound
transport
stabilization of membrane potential
regulation of ion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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