Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.
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Protein Aliases: K2P4.1 potassium channel; KT4.1b; Potassium channel subfamily K member 4; potassium channel, subfamily K, member 4; potassium channel, two pore domain subfamily K, member 4; potassium inwardly-rectifying channel subfamily K member 4; potassium inwardly-rectifying channel, subfamily K, member 4; protein expressed in male leptotene and zygotene spermatocytes 622; TRAAK; TWIK-related arachidonic acid-stimulated potassium channel protein; Two pore K(+) channel KT4.1; two pore K+ channel KT4.1; Two pore potassium channel KT4.1
Gene Aliases: K2p4.1; KCNK4; KT4.1; MLZ-622; Tex40; TRAAK; TRAAK1; TRAAKt