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KCNK4 Antibody (PA5-101761) in IHC (P)
Immunohistochemistry analysis of KCNK4 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with KCNK4 polyclonal antibody (Product # PA5-101761) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-101761
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KCNK4(Accession Q9NYG8), corresponding to amino acid residues E324-P374.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2851193
Product Specific Information
Antibody detects endogenous levels of total KCNK4.
Target Information
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: K2P4.1 potassium channel; KT4.1b; Potassium channel subfamily K member 4; potassium channel, subfamily K, member 4; potassium channel, two pore domain subfamily K, member 4; potassium inwardly-rectifying channel subfamily K member 4; potassium inwardly-rectifying channel, subfamily K, member 4; protein expressed in male leptotene and zygotene spermatocytes 622; TRAAK; TWIK-related arachidonic acid-stimulated potassium channel protein; Two pore K(+) channel KT4.1; two pore K+ channel KT4.1; Two pore potassium channel KT4.1
Gene Aliases: K2p4.1; KCNK4; KT4.1; MLZ-622; Tex40; TRAAK; TRAAK1; TRAAKt
UniProt ID: (Human) Q9NYG8, (Mouse) O88454, (Rat) G3V8V5
Entrez Gene ID: (Human) 50801, (Mouse) 16528, (Rat) 116489
potassium ion transport
memory
sensory perception of pain
stabilization of membrane potential
regulation of ion transmembrane transport
sensory perception of temperature stimulus
detection of mechanical stimulus involved in sensory perception of touch
cellular response to mechanical stimulus
cellular response to fatty acid
cellular response to alkaline pH
cellular response to temperature stimulus
potassium ion transmembrane transport
transport
ion transport
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