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Product Details
PA5-109267
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Flow Cytometry (Flow) |
1:50-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide within Human K2P41 aa 326-375 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles, store in dark |
RRID |
AB_2854678 |
Product Specific Information
Positive Control: Mouse colon tissue, rat kidney tissue, rat large intestine tissue, HepG2.
Target Information
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: K2P4.1 potassium channel; KT4.1b; Potassium channel subfamily K member 4; potassium channel, subfamily K, member 4; potassium channel, two pore domain subfamily K, member 4; TRAAK; TWIK-related arachidonic acid-stimulated potassium channel protein; Two pore K(+) channel KT4.1; two pore K+ channel KT4.1; Two pore potassium channel KT4.1
Gene Aliases: K2p4.1; KCNK4; TRAAK; TRAAK1
UniProt ID: (Human) Q9NYG8
Entrez Gene ID: (Human) 50801
Molecular Function:
ion channel
transporter
potassium ion transport
memory
sensory perception of pain
stabilization of membrane potential
regulation of ion transmembrane transport
sensory perception of temperature stimulus
detection of mechanical stimulus involved in sensory perception of touch
cellular response to mechanical stimulus
cellular response to fatty acid
cellular response to alkaline pH
cellular response to temperature stimulus
potassium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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