FIGURE: 1 / 3
Immunogen sequence: WKVSMFVEV HKAIKKRRRR RKESFESSPH SRKALQVKGS TASKDVNIFS FLSKKEETYN DLIKQIGKKA MKTSGGGETG PGPGLGPQGG GLPALPPSLV PLVVYSKNRV PTLEEVSQTL RSKGHVSRSP DEEAVARAPE DSSPAPEVFM NQLDRISEEC EPWDAQDYHP LIFQDASITF VNTEAGLSDE ETSKSSLEDN LAGEESPQQG AEAKAPLNMG EFPSSSESTF TSTESELSVP YEQLMNEYNK ANSPKGT (244-499 aa encoded by BC060793 )
KCNK5 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. KCNK5 is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport.
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Protein Aliases: Acid-sensitive potassium channel protein TASK-2; K2P5.1 potassium channel; Potassium channel subfamily K member 5; potassium channel, subfamily K, member 1 (TASK-2); potassium channel, subfamily K, member 5; potassium channel, subfamily, member 5 (KCNK5); potassium channel, two pore domain subfamily K, member 5; potassium inwardly-rectifying channel, subfamily K, member 5; TWIK-related acid-sensitive K(+) channel 2; TWIK-related acid-sensitive K+ channel 2
Gene Aliases: K2p5.1; KCNK5; KCNK5b; TASK-2; TASK2
UniProt ID: (Human) O95279