Peptide sequence: TFVNTEAGLS DEETSKSSLE DNLAGEESPQ QGAEAKAPLN MGEFPSSSES
Sequence homology: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 92%; Rat: 92%
KCNK5 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. KCNK5 is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport.
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Protein Aliases: Acid-sensitive potassium channel protein TASK-2; K2p5.1; K2P5.1 potassium channel; Potassium channel; Potassium channel subfamily K member 5; potassium channel, subfamily K, member 1 (TASK-2); potassium channel, subfamily K, member 5; potassium channel, subfamily, member 5 (KCNK5); potassium channel, two pore domain subfamily K, member 5; subfamily K member 5; TASK-2; TASK2; TWIK-related acid-sensitive K(+) channel 2; TWIK-related acid-sensitive K+ channel 2
Gene Aliases: BOS_21400; K2p5.1; KCNK5; KCNK5b; TASK-2; TASK2
UniProt ID: (Human) O95279