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Invitrogen
KCNMB2 Polyclonal Antibody
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FIGURE: 1 / 1
KCNMB2 Antibody (PA5-87770) in WB
Western blot analysis of KCNMB2 in extracts of various cell lines. Samples were incubated with KCNMB2 Polyclonal antibody (Product # PA5-87770) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-87770
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 68-194 of human KCNMB2 (NP_0058231)
Conjugate
Form
Liquid
Concentration
1.24 mg/mL
Amount
124 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TLLRSYMQSV WTEESQCTLL NASITETFNC SFSCGPDCWK LSQYPCLQVY VNLTSSGEKL LLYHTEETIK INQKCSYIPK CGKNFEESMS LVNVVMENFR KYQHFSCYSD PEGNQKSVIL TKLYSSN; Positive Samples: Mouse kidney, Mouse brain, Mouse lung, Rat brain, Rat kidney; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BK channel subunit beta-2; BKbeta2; calcium-activated potassium channel beta 2; Calcium-activated potassium channel subunit beta-2; Calcium-activated potassium channel, subfamily M subunit beta-2; Charybdotoxin receptor subunit beta-2; K(VCA)beta-2; Maxi K channel subunit beta-2; potassium large conductance calcium-activated channel, subfamily M, beta member 2; Rbeta3; Slo-beta-2; Slo-beta2
Gene Aliases: 2700049B16Rik; 3110031N04Rik; Kcmb2; Kcnmb2
UniProt ID: (Mouse) Q9CZM9, (Rat) Q811Q0
Entrez Gene ID: (Mouse) 72413, (Rat) 294961
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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