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Proteintech
KDM2A Polyclonal Antibody
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Product Details
24311-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KDM2A Fusion Protein Ag19448 (374-558 aa encoded by BC064360)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DEEAVDREP RRLSSRRSVL TSPVANGVNL DYDGLGKTCR SLPSLKKTLA GDSSSDCSRG SHNGQVWDPQ CAPRKDRQVH LTHFELEGLR CLVDKLESLP LHKKCVPTGI EDEDALIADV KILLEELANS DPKLALTGVP IVQWPKRDKL KFPTRPKVRV PTIPITKPHT MKPAPRLTPV RPAAAS (374-558 aa encoded by BC064360)
Target Information
FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box). The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: [Histone-H3]-lysine-36 demethylase 1A; CXXC-type zinc finger protein 8; DKFZp434M1735; F-box and leucine-rich repeat protein 11; F-box protein containing leucine repeats; F-box protein FBL7; F-box protein Lilina; F-box/LRR-repeat protein 11; FLJ00115; FLJ46431; JmjC domain-containing histone demethylation protein 1A; jumonji C domain-containing histone demethylase 1A; KDM2A-C620; KDM2A-delta N; KDM2A-N782; lysine (K)-specific demethylase 2A; Lysine-specific demethylase 2A; SF-KDM2A; unnamed protein product
Gene Aliases: 100043628; 5530401A10Rik; AA589516; AW536790; CXXC8; FBL11; FBL7; FBXL11; Gm4560; Jhdm1; JHDM1A; KDM2A; KIAA1004; lalina; LILINA
UniProt ID: (Human) Q9Y2K7, (Mouse) P59997
Entrez Gene ID: (Human) 22992, (Mouse) 225876
double-strand break repair via nonhomologous end joining
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
oxidation-reduction process
histone H3-K36 demethylation
chromatin organization
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
negative regulation of transcription by competitive promoter binding
circadian regulation of gene expression
regulation of circadian rhythm
rhythmic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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