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          • Primary Antibodies ›
          • KDM2A Antibodies

          Invitrogen

          KDM2A Polyclonal Antibody

          View all (11) KDM2A antibodies

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          Cite KDM2A Polyclonal Antibody

          • Antibody Testing Data (4)
          KDM2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          KDM2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          KDM2A Antibody (PA5-144674) in IHC (P)

          Immunohistochemistry of KDM2A in paraffin-embedded human stomach tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with KDM2A polyclonal antibody (Product # PA5-144674) with a dilution of 1:1,000 for 1 hour at room temper... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          KDM2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KDM2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KDM2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KDM2A Antibody in Western Blot (WB)
          KDM2A Polyclonal Antibody

          Product Details

          PA5-144674

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein within human KDM2A aa 381-580/ 1162.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 0.1% BSA, 40% glycerol

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3093613

          Product Specific Information

          Positive control: MCF-7 cell lysate, Jurkat cell lysate, PC-12 cell lysate, human brain tissue lysate, rat colon tissue, human stomach tissue, mouse colon tissue.

          Predicted band size: 133 kDa

          Subcellular Location: Nucleus, nucleoplasm, Chromosome.

          Target Information

          FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box). The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: [Histone-H3]-lysine-36 demethylase 1A; CXXC-type zinc finger protein 8; DKFZp434M1735; F-box and leucine-rich repeat protein 11; F-box protein containing leucine repeats; F-box protein FBL7; F-box protein Lilina; F-box/LRR-repeat protein 11; FLJ00115; FLJ46431; JmjC domain-containing histone demethylation protein 1A; jumonji C domain-containing histone demethylase 1A; lysine (K)-specific demethylase 2A; Lysine-specific demethylase 2A; SF-KDM2A

          View more View less

          Gene Aliases: 100043628; 5530401A10Rik; AA589516; AW536790; CXXC8; FBL11; FBL7; FBXL11; Gm4560; Jhdm1; JHDM1A; KDM2A; KIAA1004; lalina; LILINA

          View more View less

          UniProt ID: (Human) Q9Y2K7, (Mouse) P59997

          View more View less

          Entrez Gene ID: (Human) 22992, (Mouse) 225876, (Rat) 361700

          View more View less

          Function(s)
          DNA binding zinc ion binding histone demethylase activity histone demethylase activity (H3-K36 specific) oxidoreductase activity unmethylated CpG binding metal ion binding dioxygenase activity
          Process(es)
          double-strand break repair via nonhomologous end joining transcription, DNA-templated regulation of transcription, DNA-templated oxidation-reduction process histone H3-K36 demethylation chromatin modification
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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