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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • JMJD2C Antibodies

          Active Motif

          KDM4C Polyclonal Antibody

          View all (16) JMJD2C antibodies

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          Cite KDM4C Polyclonal Antibody

          • Antibody Testing Data (1)
          KDM4C Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          KDM4C Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          KDM4C Antibody (61687) in WB

          KDM4C antibody (pAb) tested by Western blot. COS-7 nuclear extract (25 µg per lane) was probed with KDM4C pAb at a 1:500 dilution. Lane 1: No treatment. Lane 2: Cells treated with CoCl2. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          KDM4C Antibody in Western Blot (WB)
          KDM4C Polyclonal Antibody

          Product Details

          61687

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500
          -
          Product Specifications

          Species Reactivity

          Human, Non-human primate

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          This antibody was raised against a peptide within human kDM4C.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Purification

          Antigen affinity chromatography, Affinity chromatography

          Storage buffer

          PBS, pH 7.5, with 30% glycerol

          Contains

          0.035% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2793735

          Target Information

          Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 "Lys-9' and H3 "Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: [histone H3]-trimethyl-L-lysine(9) demethylase 4C; bA146B14.1; GASC-1 protein; Gene amplified in squamous cell carcinoma 1 protein; JmjC domain-containing histone demethylation protein 3C; Jumonji domain-containing protein 2C; lysine (K)-specific demethylase 4C; Lysine-specific demethylase 4C; RP11-169L18.1; tudor domain containing 14C

          View more View less

          Gene Aliases: GASC1; JHDM3C; JMJD2C; KDM4C; KIAA0780; TDRD14C

          View more View less

          UniProt ID: (Human) Q9H3R0

          View more View less

          Entrez Gene ID: (Human) 23081

          View more View less

          Function(s)
          zinc ion binding enzyme binding histone demethylase activity histone demethylase activity (H3-K9 specific) androgen receptor binding dioxygenase activity histone modifying enzyme
          Process(es)
          transcription, DNA-templated regulation of transcription from RNA polymerase II promoter positive regulation of cell proliferation histone H3-K9 demethylation oxidation-reduction process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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