Recommended positive controls: SK-N-SH, IMR32, SK-N-AS.
Predicted reactivity: Mouse (93%), Xenopus laevis (82%), Dog (86%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4lysine (K)-specific demethylase 6A; [histone H3]-trimethyl-L-lysine(27) demethylase 6A; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)); Histone demethylase UTX; lysine (K)-specific demethylase 6A; Lysine-specific demethylase 6A; ubiquitously transcribed tetratricopeptide repeat gene, X chromosome; ubiquitously transcribed tetratricopeptide repeat protein X-linked; Ubiquitously transcribed TPR protein on the X chromosome; Ubiquitously transcribed X chromosome tetratricopeptide repeat protein; ubiquitously-transcribed TPR gene on the X chromosome; Ubiquitously-transcribed TPR protein on the X chromosome; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein
Gene Aliases: bA386N14.2; KABUK2; KDM6A; UTX
Molecular Function: chromatin/chromatin-binding, or -regulatory protein