PA5-31828 targets KDM6A in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31828 immunogen is recombinant fragment corresponding to a region within amino acids 409 and 750 of Human KDM6A.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3.
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Protein Aliases: bA386N14.2; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)); Histone demethylase UTX; KABUK2; lysine (K)-specific demethylase 6A; Lysine-specific demethylase 6A; ubiquitously transcribed tetratricopeptide repeat protein X-linked; ubiquitously transcribed TPR protein on the X chromosome; ubiquitously transcribed X chromosome tetratricopepti; ubiquitously-transcribed TPR gene on the X chromosome; Ubiquitously-transcribed TPR protein on the X chromosome; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein; UTX
Gene Aliases: bA386N14.2; KABUK2; KDM6A; UTX
UniProt ID: (Human) O15550
Entrez Gene ID: (Human) 7403
Molecular Function: transcription factor