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Product Details
PA5-51521
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KDM6A
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642983
Product Specific Information
Immunogen sequence: SNSCILLDKC PPPRPPTSPY PPLPKDKLNP PTPSIYLENK RDAFFPPLHQ FCTNPKNPVT VIRGLAGALK LDLGLFSTKT LVEANNEHMV EVRTQLLQPA DENWDPTGTK KIWRCESNRS HTTI
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [histone H3]-trimethyl-L-lysine(27) demethylase 6A; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)); Histone demethylase UTX; lysine (K)-specific demethylase 6A; Lysine-specific demethylase 6A; ubiquitously transcribed tetratricopeptide repeat protein X-linked; ubiquitously-transcribed TPR gene on the X chromosome; Ubiquitously-transcribed TPR protein on the X chromosome; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein
Gene Aliases: bA386N14.2; KABUK2; KDM6A; UTX
UniProt ID: (Human) O15550
Entrez Gene ID: (Human) 7403
in utero embryonic development
neural tube closure
heart morphogenesis
respiratory system process
positive regulation of gene expression
somite rostral/caudal axis specification
multicellular organism growth
mesodermal cell differentiation
notochord morphogenesis
histone H3-K4 methylation
oxidation-reduction process
canonical Wnt signaling pathway
histone H3-K27 demethylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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