Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: QGAPLLSTPK RERMVLMKTV EEKDLEIERL KTKQKELEAK MLAQKAEEKE NHCPTMLRPL SHRTVTGAKP LKKAVVMPLQ LIQEQAASPN AEIHILKNKG RKRKLESLDA LEPEEKAEDC WELQISPELL AHGRQKILDL LNEGSARDLR SLQRIGPKKA QLIVGWRELH GPFSQVEDLE RVEGITGKQM ESFLKANILG LAAGQRCGAS; Positive Samples: A431, 293T, U-87MG, A549, HeLa, Jurkat, Mouse testis; Cellular Location: Cytoplasm, Nucleus, cytoskeleton
The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance.
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Protein Aliases: kinesin family member 22A; kinesin-like 4; Kinesin-like DNA-binding protein; kinesin-like DNA-binding protein pseudogene; Kinesin-like protein 4; Kinesin-like protein KIF22; origin of plasmid DNA replication-binding protein; oriP binding protein
Gene Aliases: A-328A3.2; AU021460; C81217; KID; KIF22; Kif22a; KNSL4; OBP; OBP-1; OBP-2; SEMDJL2
UniProt ID: (Human) B7Z265, (Mouse) Q3V300
Entrez Gene ID: (Human) 3835, (Mouse) 110033
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