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Proteintech
KIDINS220 Polyclonal Antibody
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Product Details
21856-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KIDINS220 Fusion Protein Ag16448 (1374-1672 aa encoded by BC130610)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LDPITEEDE KSDQSGSKLL PGKKSSERSS LFQTDLKLKG SGLRYQKLPS DEDESGTEES DNTPLLKDDK DRKAEGKVER VPKSPEHSAE PIRTFIKAKE YLSDALLDKK DSSDSGVRSS ESSPNHSLHN EVADDSQLEK ANLIELEDDS HSGKRGIPHS LSGLQDPIIA RMSICSEDKK SPSECSLIAS SPEENWPACQ KAYNLNRTPS TVTLNNNSAP ANRANQNFDE MEGIRETSQV ILRPSSSPNP TTIQNENLKS MTHKRSQRSS YTRLSKDPPE LHAAASSEST GFGEERESIL (1374-1672 aa encoded by BC130610)
Target Information
This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ankyrin repeat-rich membrane-spanning protein; kinase D-interacting substrate 220kDa; Kinase D-interacting substrate of 220 kDa; MGC163482; unnamed protein product
Gene Aliases: ARMS; KIAA1250; KIDINS220; SINO; VENARG
UniProt ID: (Human) Q9ULH0
Entrez Gene ID: (Human) 57498
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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