Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MQRTFAWLL DRVQHLGAPV TLRASYLEIY NEQVRDLLSL GSPRPLPVRW NKTRGFYVEQ LRVVEFGSLE ALMELLQTGL SRRRNSAHTL NQASSRSHAL LTLYISRQTA QQMPSVDPGE PPVGGKLCFV DLAGSEKVAA TGSRGELMLE ANSINRSLLA LGHCISLLLD PQRKQSHIPF RDSKLTKLLA DSLGGRGVTL MVACVSPSAQ CLPETLSTLR YASRAQRVTT RPQAPKSPVA KQPQRLETEM LQLQEENRRL QFQLDQMDCK ASGLSGARVA WAQRNLYGML QEFMLENERL RKEKSQLQNS RDLAQNEQRI LAQQVHALER RLLSA (1-334 aa encoded by BC010626)
KIF12 encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: kinesin 12; kinesin superfamily protein 12; Kinesin-like protein KIF12; N-9 kinesin; RP1156P10.3
Gene Aliases: KIF12
UniProt ID: (Human) Q96FN5, (Mouse) Q9D2Z8
Entrez Gene ID: (Human) 113220, (Rat) 313254, (Mouse) 16552
Molecular Function:
microtubule binding motor protein
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