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This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants.
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Protein Aliases: homolog of mouse KIF13A mannose-6-phosphate receptor transporter; kinesin 13A; Kinesin-like protein KIF13A; Kinesin-like protein RBKIN; N-3 kinesin
Gene Aliases: 4930505I07Rik; bA500C11.2; KIF13A; mKIAA4109; RBKIN
UniProt ID: (Human) Q9H1H9
Entrez Gene ID: (Human) 63971, (Mouse) 16553, (Rat) 308173
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