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Invitrogen
KIF1A Polyclonal Antibody
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Product Details
PA5-40801
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human KIF1A (aa 35-84).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: TTIVNPKQPK ETPKSFSFDY SYWSHTSPED INYASQKQVY RDIGEEMLQH
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%; Yeast: 100%; Zebrafish: 79%
Target Information
KIF1A is the motor for anterograde axonal transport of synaptic vesicle precursors.The protein encoded by this gene is a member of the kinesin family. This protein is highly similar to mouse heavy chain kinesin member 1A protein which is an anterograde motor protein that transports membranous organelles along axonal microtubules. It is thought that this protein may play a critical role in the development of axonal neuropathies resulting from impaired axonal transport. There are multiple polyadenylation sites found in this gene. Sequence Note: X90840.1 is a chimeric sequence. Only the ATSV region was propagated into this RefSeq record. [6/26/03, RefSeq staff]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Axonal transporter of synaptic vesicles; DKFZp686I2094; FLJ30229; hUnc-104; kinesin, heavy chain, member 1A, homolog of mouse; Kinesin-like protein KIF1A; member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules; mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC; MGC133285; MGC133286; Microtubule-based motor KIF1A; putative; Unc-104- and KIF1A-related protein
Gene Aliases: ATSV; C2orf20; HSN2C; KIF1A; MRD9; NESCAVS; SPG30; SPG30A; SPG30B; UNC104
UniProt ID: (Human) Q12756
Entrez Gene ID: (Human) 547
microtubule-based movement
anterograde axonal transport
transport along microtubule
vesicle-mediated transport
regulation of dendritic spine development
regulation of dendritic spine morphogenesis
dense core granule cytoskeletal transport
anterograde neuronal dense core vesicle transport
retrograde neuronal dense core vesicle transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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