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KIF26B Polyclonal Antibody

KIF26B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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KIF26B Antibody (17422-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 17422-1-AP (KIF26B Antibody) at dilution of 1:200 (under 40x lens).

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Product Details

17422-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Product Specifications

Species Reactivity

Dog, Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KIF26B Fusion Protein Ag11446 (151-355 aa encoded by BC042481)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.31 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: AFSAVIHDK LQVPNTIRKA WNDRDNRCDI CATHLNQLKQ EAIQMVLTLE QAAGSEHYDA SPCSPPPLSN IPTLVGSRHV GGLQQPRDWA FVPAPCATSN YTGFANKHGS KPSSLGVSNG AEKKSGSPTH QAKVSLQMAT SPSNGNILNS VAIQAHQYLD GTWSLSRTNG VTLYPYQDSE ALVTRGRGRL EDSAAAPALM SEDRGA (151-355 aa encoded by BC042481)

Target Information

KIF26B is a member of kinesin-11 family and plays important role in embryogenesis. It is a downstream target of Sall1 and is essential for kidney development. KIF26B is also involved in tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth.

Cancer research

Wang K,Ma F,Arai S,Wang Y,Varkaris A,Poluben L,Voznesensky O,Xie F,Zhang X,Yuan X,Balk SP

Tue Apr 04 00:00:00 UTC 2023

Deactivation of AKT/GSK-3β-mediated Wnt/β-catenin pathway by silencing of KIF26B weakens the malignant behaviors of non-small cell lung cancer.

Tissue & cell

Chen N,Wu Q,Zhang G,Fu J,Geng Q,Zhang Y

Wed Jun 01 00:00:00 UTC 2022

The Kinesin Gene KIF26B Modulates the Severity of Post-Traumatic Heterotopic Ossification.

International journal of molecular sciences

Pickering GAE,Felix-Ilemhenbhio F,Clark MJ,Kocsy K,Simpson J,Bellantuono I,Gartland A,Wilkinson JM,Hatzikotoulas K,Kiss-Toth E

Tue Aug 16 00:00:00 UTC 2022

KIF26B Is Overexpressed in Medulloblastoma and Promotes Malignant Progression by Activating the PI3K/AKT Pathway.

Analytical cellular pathology (Amsterdam)

Liu Y,Zhang X,Pan R,Liang X,Liu Q,Yang C,Li X

Mon Jul 25 00:00:00 UTC 2022

KIF26B Is Overexpressed in Medulloblastoma and Promotes Malignant Progression by Activating the PI3K/AKT Pathway.

Analytical cellular pathology (Amsterdam)

Liu Y,Zhang X,Pan R,Liang X,Liu Q,Yang C,Li X

Mon Jul 25 00:00:00 UTC 2022

KIF26B Silencing Prevents Osseous Transdifferentiation of Progenitor/Stem Cells and Attenuates Ectopic Calcification in a Murine Model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Yan M,Duan X,Cai L,Zhang W,Silva MJ,Brophy RH,Rai MF

Tue Feb 01 00:00:00 UTC 2022

KIF26B Silencing Prevents Osseous Transdifferentiation of Progenitor/Stem Cells and Attenuates Ectopic Calcification in a Murine Model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Yan M,Duan X,Cai L,Zhang W,Silva MJ,Brophy RH,Rai MF

Tue Feb 01 00:00:00 UTC 2022

KIF26B Silencing Prevents Osseous Transdifferentiation of Progenitor/Stem Cells and Attenuates Ectopic Calcification in a Murine Model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Yan M,Duan X,Cai L,Zhang W,Silva MJ,Brophy RH,Rai MF

Tue Feb 01 00:00:00 UTC 2022

KIF26B Silencing Prevents Osseous Transdifferentiation of Progenitor/Stem Cells and Attenuates Ectopic Calcification in a Murine Model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Yan M,Duan X,Cai L,Zhang W,Silva MJ,Brophy RH,Rai MF

Tue Feb 01 00:00:00 UTC 2022

Novel mechanistic role of Kif26b in adipogenic differentiation of murine multipotent stromal cells.

Biochemical and biophysical research communications

Yan M,Cai L,Duan X,Rai MF

Sat Feb 12 00:00:00 UTC 2022

Fusobacterium nucleatum reduces METTL3-mediated m⁶A modification and contributes to colorectal cancer metastasis.

Nature communications

Chen S,Zhang L,Li M,Zhang Y,Sun M,Wang L,Lin J,Cui Y,Chen Q,Jin C,Li X,Wang B,Chen H,Zhou T,Wang L,Hsu CH,Zhuo W

Thu Mar 10 00:00:00 UTC 2022

Fusobacterium nucleatum reduces METTL3-mediated m⁶A modification and contributes to colorectal cancer metastasis.

Nature communications

Chen S,Zhang L,Li M,Zhang Y,Sun M,Wang L,Lin J,Cui Y,Chen Q,Jin C,Li X,Wang B,Chen H,Zhou T,Wang L,Hsu CH,Zhuo W

Thu Mar 10 00:00:00 UTC 2022

Fusobacterium nucleatum reduces METTL3-mediated m⁶A modification and contributes to colorectal cancer metastasis.

Nature communications

Chen S,Zhang L,Li M,Zhang Y,Sun M,Wang L,Lin J,Cui Y,Chen Q,Jin C,Li X,Wang B,Chen H,Zhou T,Wang L,Hsu CH,Zhuo W

Thu Mar 10 00:00:00 UTC 2022

Fusobacterium nucleatum reduces METTL3-mediated m⁶A modification and contributes to colorectal cancer metastasis.

Nature communications

Chen S,Zhang L,Li M,Zhang Y,Sun M,Wang L,Lin J,Cui Y,Chen Q,Jin C,Li X,Wang B,Chen H,Zhou T,Wang L,Hsu CH,Zhuo W

Thu Mar 10 00:00:00 UTC 2022

Ginsenoside Rh2 reduces m6A RNA methylation in cancer via the KIF26B-SRF positive feedback loop.

Journal of ginseng research

Hu C,Yang L,Wang Y,Zhou S,Luo J,Gu Y

Mon Nov 01 00:00:00 UTC 2021

ELK1-induced up-regulation of KIF26B promotes cell cycle progression in breast cancer.

Medical oncology (Northwood, London, England)

Wang S,Zhang H,Liu H,Guo X,Ma R,Zhu W,Gao P

Wed Nov 24 00:00:00 UTC 2021

ELK1-induced up-regulation of KIF26B promotes cell cycle progression in breast cancer.

Medical oncology (Northwood, London, England)

Wang S,Zhang H,Liu H,Guo X,Ma R,Zhu W,Gao P

Wed Nov 24 00:00:00 UTC 2021

KIF26B promotes cell proliferation and migration through the FGF2/ERK signaling pathway in breast cancer.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Teng Y,Guo B,Mu X,Liu S

Sat Dec 01 00:00:00 UTC 2018

KIF26B promotes cell proliferation and migration through the FGF2/ERK signaling pathway in breast cancer.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Teng Y,Guo B,Mu X,Liu S

Sat Dec 01 00:00:00 UTC 2018

KIF26B promotes cell proliferation and migration through the FGF2/ERK signaling pathway in breast cancer.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Teng Y,Guo B,Mu X,Liu S

Sat Dec 01 00:00:00 UTC 2018

KIF26B promotes cell proliferation and migration through the FGF2/ERK signaling pathway in breast cancer.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Teng Y,Guo B,Mu X,Liu S

Sat Dec 01 00:00:00 UTC 2018

MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene.

Cancer cell international

Pu Y,Yi Q,Zhao F,Wang H,Cai W,Cai S

Mon Aug 08 00:00:00 UTC 2016

MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene.

Cancer cell international

Pu Y,Yi Q,Zhao F,Wang H,Cai W,Cai S

Mon Aug 08 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: Kinesin-like protein KIF26B

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Gene Aliases: KIF26B

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UniProt ID: (Human) Q2KJY2

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Entrez Gene ID: (Dog) 490379, (Human) 55083

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Function(s)

ATP binding microtubule binding ATP-dependent microtubule motor activity, plus-end-directed microtubule binding motor protein

Process(es)

microtubule-based movement axon guidance protein localization positive regulation of cell-cell adhesion establishment of cell polarity cytoskeleton-dependent intracellular transport ureteric bud invasion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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KIF26B Polyclonal Antibody

KIF26B Antibody (17422-1-AP) in IHC (P)

Product Details

17422-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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