Immunogen sequence: AVPEDEQIS AKDQKNLEPC DNTPIIDNIA PVVAGISTEE KEKYDEEISS LYR (143-194 aa encoded by BC110287)
Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Kinesin heavy chain isoform 5C; kinesin heavy chain member 5C; Kinesin heavy chain neuron-specific 2; Kinesin-1
Gene Aliases: CDCBM2; Khc; KIAA0531; KIF5C; KINN; NKHC; NKHC-2; NKHC2
Molecular Function: microtubule binding motor protein