Proteintech

KIFC3 Polyclonal Antibody

View all (6) KIFC3 antibodies

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KIFC3 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10125-2-AP (KIFC3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

KIFC3 Antibody in Western Blot (WB) — Mouse lung tissue were subjected to SDS PAGE followed by western blot with 10125-2-AP (KIFC3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

KIFC3 Antibody in Immunoprecipitation (IP) — IP result of anti-KIFC3 (IP:10125-2-AP, 4ug; Detection:10125-2-AP 1:500) with mouse kidney tissue lysate 7200ug.

Product Details

10125-2-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	View 4 publications 4 publications
Immunocytochemistry (ICC/IF)	Assay-dependent	-
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Artificial Control, Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	KIFC3 Fusion Protein Ag0172 (73-314 aa encoded by BC001211) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.22 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: ARSAARPAL AQCRALSVDW AGPGSPHGLY LTLQVEHLKE KLISQAQEVS RLRSELGGTD LEKHRDLLMV ENERLRQEMR RCEAELQELR TKPAGPCPGC EHSQESAQLR DKLSQLQLEM AESKGMLSEL NLEVQQKTDR LAEVELRLKD CLAEKAQEEE RLSRRLRDSH ETIASLRAQS PPVKYVIKTV EVESSKTKQA LSESQARNQH LQEQVAMQRQ VLKEMEQQLQ SSHQLTARLR AQI (73-314 aa encoded by BC001211)

Target Information

KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 ).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.

Biochimica et biophysica acta

Dietrich D,Seiler F,Essmann F,Dodt G

Sun Dec 01 00:00:00 EST 2013

Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.

Biochimica et biophysica acta

Dietrich D,Seiler F,Essmann F,Dodt G

Sun Dec 01 00:00:00 EST 2013

Overexpression of kinesins mediates docetaxel resistance in breast cancer cells.

Cancer research

De S,Cipriano R,Jackson MW,Stark GR

Thu Oct 15 00:00:00 EDT 2009

The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets.

Biochimica et biophysica acta

Kovacevic Z,Fu D,Richardson DR

Wed Oct 01 00:00:00 EDT 2008

Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver.

Molecular biology of the cell

Nath S,Bananis E,Sarkar S,Stockert RJ,Sperry AO,Murray JW,Wolkoff AW

Tue May 01 00:00:00 EDT 2007

Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver.

Molecular biology of the cell

Nath S,Bananis E,Sarkar S,Stockert RJ,Sperry AO,Murray JW,Wolkoff AW

Tue May 01 00:00:00 EDT 2007

Bioinformatics

Protein Aliases: DKFZp686D23201; Kinesin-like protein KIFC3

Gene Aliases: AI325457; BB123200; KIFC3; KRP4

UniProt ID: (Human) Q9BVG8, (Mouse) O35231

Entrez Gene ID: (Human) 3801, (Mouse) 16582, (Rat) 307644

Molecular Function: microtubule binding motor protein

microtubule-based movement Golgi organization visual perception zonula adherens maintenance epithelial cell-cell adhesion microtubule-based process metabolic process

Process(es)

microtubule motor activity protein binding ATP binding microtubule binding ATP-dependent microtubule motor activity, minus-end-directed ATPase activity nucleotide binding