Proteintech

KIFC3 Polyclonal Antibody

View all (7) KIFC3 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (3)

KIFC3 Antibody in Western Blot (WB)

KIFC3 Antibody in Western Blot (WB)

FIGURE: 1 / 3

KIFC3 Antibody (10125-2-AP) in WB

Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10125-2-AP (KIFC3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

KIFC3 Antibody in Western Blot (WB)

KIFC3 Antibody in Western Blot (WB)

KIFC3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

KIFC3 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10125-2-AP (KIFC3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

KIFC3 Antibody in Western Blot (WB) — Mouse lung tissue were subjected to SDS PAGE followed by western blot with 10125-2-AP (KIFC3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

KIFC3 Antibody in Immunoprecipitation (IP) — IP result of anti-KIFC3 (IP:10125-2-AP, 4ug; Detection:10125-2-AP 1:500) with mouse kidney tissue lysate 7200ug.

Product Details

10125-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KIFC3 Fusion Protein Ag0172 (73-314 aa encoded by BC001211)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.22 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: ARSAARPAL AQCRALSVDW AGPGSPHGLY LTLQVEHLKE KLISQAQEVS RLRSELGGTD LEKHRDLLMV ENERLRQEMR RCEAELQELR TKPAGPCPGC EHSQESAQLR DKLSQLQLEM AESKGMLSEL NLEVQQKTDR LAEVELRLKD CLAEKAQEEE RLSRRLRDSH ETIASLRAQS PPVKYVIKTV EVESSKTKQA LSESQARNQH LQEQVAMQRQ VLKEMEQQLQ SSHQLTARLR AQI (73-314 aa encoded by BC001211)

Target Information

KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 ).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

KIFC3 regulates progression of hepatocellular carcinoma via EMT and the AKT/mTOR pathway.

Experimental cell research

Lu S,Liu Y,Tian S,He Y,Dong W

Mon May 01 00:00:00 UTC 2023

Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.

The EMBO journal

Miyamoto T,Hosoba K,Itabashi T,Iwane AH,Akutsu SN,Ochiai H,Saito Y,Yamamoto T,Matsuura S

Wed Jun 17 00:00:00 UTC 2020

Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.

Biochimica et biophysica acta

Dietrich D,Seiler F,Essmann F,Dodt G

Sun Dec 01 00:00:00 UTC 2013

Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.

Biochimica et biophysica acta

Dietrich D,Seiler F,Essmann F,Dodt G

Sun Dec 01 00:00:00 UTC 2013

Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.

Biochimica et biophysica acta

Dietrich D,Seiler F,Essmann F,Dodt G

Sun Dec 01 00:00:00 UTC 2013

Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.

Biochimica et biophysica acta

Dietrich D,Seiler F,Essmann F,Dodt G

Sun Dec 01 00:00:00 UTC 2013

Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.

Biochimica et biophysica acta

Dietrich D,Seiler F,Essmann F,Dodt G

Sun Dec 01 00:00:00 UTC 2013

Overexpression of kinesins mediates docetaxel resistance in breast cancer cells.

Cancer research

De S,Cipriano R,Jackson MW,Stark GR

Thu Oct 15 00:00:00 UTC 2009

Overexpression of kinesins mediates docetaxel resistance in breast cancer cells.

Cancer research

De S,Cipriano R,Jackson MW,Stark GR

Thu Oct 15 00:00:00 UTC 2009

The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets.

Biochimica et biophysica acta

Kovacevic Z,Fu D,Richardson DR

Wed Oct 01 00:00:00 UTC 2008

The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets.

Biochimica et biophysica acta

Kovacevic Z,Fu D,Richardson DR

Wed Oct 01 00:00:00 UTC 2008

Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver.

Molecular biology of the cell

Nath S,Bananis E,Sarkar S,Stockert RJ,Sperry AO,Murray JW,Wolkoff AW

Tue May 01 00:00:00 UTC 2007

Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver.

Molecular biology of the cell

Nath S,Bananis E,Sarkar S,Stockert RJ,Sperry AO,Murray JW,Wolkoff AW

Tue May 01 00:00:00 UTC 2007

Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver.

Molecular biology of the cell

Nath S,Bananis E,Sarkar S,Stockert RJ,Sperry AO,Murray JW,Wolkoff AW

Tue May 01 00:00:00 UTC 2007

Bioinformatics

Protein Aliases: DKFZp686D23201; Kinesin-like protein KIFC3

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Gene Aliases: AI325457; BB123200; KIFC3; KRP4

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UniProt ID: (Human) Q9BVG8, (Mouse) O35231

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Entrez Gene ID: (Human) 3801, (Mouse) 16582, (Rat) 307644

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microtubule motor activity protein binding ATP binding microtubule binding ATP-dependent microtubule motor activity, minus-end-directed ATPase activity nucleotide binding microtubule binding motor protein

microtubule-based movement Golgi organization visual perception zonula adherens maintenance epithelial cell-cell adhesion microtubule-based process metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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