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      KIFC3 Polyclonal Antibody

      See 2 other KIFC3 antibodies ›
      KIFC3 Polyclonal Antibody for Western Blot, IF, ICC and IHC (P)

      Catalog#: PA5-30074 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      PA5-30074 100 µL
      349.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

      Anti-Rabbit Secondary Antibodies (263)
      Alexa Fluor® Anti-Rabbit Secondary Antibodies (69)
      HRP Anti-Rabbit Secondary Antibodies (30)

      Product Details

      References

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Published species reactivity Human
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen Recombinant fragment corresponding to a region within amino acids 51 and 294 of Human KIFC3
      Conjugate Unconjugated
      Form Liquid
      Concentration 1 mg/ml
      Purification Antigen affinity chromatography
      Storage buffer 0.1M tris glycine, pH 7, with 20% glycerol
      Contains 0.01% thimerosal
      Storage Conditions -20° C, Avoid Freeze/Thaw Cycles
      Tested Applications Dilution *
      Immunocytochemistry (ICC) 1:100-1:1000
      Immunofluorescence (IF) 1:100-1:1000
      Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
      Western Blot (WB) 1:500-1:3000

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Published Applications
      Immunocytochemistry (ICC) See 1 publications below

      Product Specific Information

      PA5-30074 targets KIFC3 in IF, IHC (P), and WB applications and shows reactivity with Human samples.

      The PA5-30074 immunogen is recombinant fragment corresponding to a region within amino acids 51 and 294 of Human KIFC3.

      Background/Target Information

      KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 [PubMed 9782090]).

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      References

      Immunocytochemistry

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Human Not Cited KIFC3 promotes mitotic progression and integrity of the central spindle in cytokinesis.
      PA5-30074 was used in immunocytochemistry and western blot to demonstrate that KIFC3 is important for central bridge morphology       		Nachbar J,Lázaro-Diéguez F,Prekeris R,Cohen D,Müsch A Cell cycle (Georgetown, Tex.) (13:426) 2014

      Documents

      Material safety data sheets (MSDS)

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