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| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide taken within amino acid region 600-650 on mouse Neph1 protein. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5-1.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ10845; kin of IRRE like 1; Kin of IRRE-like protein 1; Kin of irregular chiasm-like protein 1; MGC129542; MGC129543; nephrin 1; nephrin related; Nephrin-like protein 1
Gene Aliases: 6720469N11Rik; KIRREL; KIRREL1; NEPH1
UniProt ID: (Human) Q96J84, (Rat) Q6X936, (Mouse) Q80W68
Entrez Gene ID: (Human) 55243, (Rat) 310695, (Mouse) 170643
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