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          • Primary Antibodies ›
          • KIRREL Antibodies

          Fabgennix

          KIRREL Polyclonal Antibody, FITC

          View all (15) KIRREL antibodies

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          Cite KIRREL Polyclonal Antibody, FITC

          Additional Information:
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          KIRREL Polyclonal Antibody, FITC

          Product Details

          NEPH1-N-FITC

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 200-250 on mouse Neph1 protein.
          3D Epitope / Immunogen

          Conjugate

          FITC FITC FITC

          Excitation/Emission Max

          498/517 nm View spectra spectra

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FLJ10845; kin of IRRE like 1; Kin of IRRE-like protein 1; Kin of irregular chiasm-like protein 1; MGC129542; MGC129543; nephrin 1; Nephrin-like protein 1

          View more View less

          Gene Aliases: 6720469N11Rik; Kirrel; Kirrel1; Neph1

          View more View less

          UniProt ID: (Rat) Q6X936, (Mouse) Q80W68

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          Entrez Gene ID: (Rat) 310695, (Mouse) 170643

          View more View less

          Function(s)
          protein binding myosin binding
          Process(es)
          negative regulation of protein phosphorylation excretion single organismal cell-cell adhesion positive regulation of actin filament polymerization
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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