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Proteintech
KIRREL2 Polyclonal Antibody
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Product Details
10890-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KIRREL2 Fusion Protein Ag1036 (1-219 aa encoded by BC007312)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLRMRVPAL LVLLFCFRGR AGPSPHFLQQ PEDLVVLLGE GGAQASLGRR ASASFSEQKN LMRIPGSSDG SSSRGPEEEE TGSREDRGPI VHTDHSDLVL EEEGTLETKD PTNGYYKVRG VSVSLSLGEA PGGGLFLPPP SPLGPPGTPT FYDFNPHLGM VPPCRLYRAR AGYLTTPHPR AFTSYIKPTS FGPPDLAPGT PPFPYAAFPT PSHPRLQTHV (1-219 aa encoded by BC007312)
Target Information
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp564A1164; Kin of IRRE-like protein 2; kin of irregular chiasm-like 2; Kin of irregular chiasm-like protein 2; MGC15718; nephrin-like 3; nephrin-like gene 1; Nephrin-like protein 3; X kin of IRRE like 2
Gene Aliases: C330019F22Rik; FILTRIN; KIRREL2; NEPH3; NLG1; UNQ5827/PRO19646
UniProt ID: (Human) Q6UWL6, (Mouse) Q7TSU7
Entrez Gene ID: (Human) 84063, (Rat) 100359836, (Mouse) 243911
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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