Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
KLC1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
19028-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLC1 Fusion Protein Ag13570 (1-290 aa encoded by BC008881)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MYDNMSTMV YIKEDKLEKL TQDEIISKTK QVIQGLEALK NEHNSILQSL LETLKCLKKD DESNLVEEKS NMIRKSLEML ELGLSEAQVM MALSNHLNAV ESEKQKLRAQ VRRLCQENQW LRDELANTQQ KLQKSEQSVA QLEEEKKHLE FMNQLKKYDD DISPSEDKDT DSTKEPLDDL FPNDEDDPGQ GIQQQHSSAA AAAQQGGYEI PARLRTLHNL VIQYASQGRY EVAVPLCKQA LEDLEKTSGH DHPDVATMLN ILALVYRDQN KYKDAANLLN DALAIREKTL G (1-290 aa encoded by BC008881)
Target Information
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: kinesin 2; kinesin 2 60/70kDa; Kinesin light chain 1; Kinesin2; KLC 1; KNS 2; KNS 2A; medulloblastoma antigen MU-MB-2.50; MGC15245
Gene Aliases: AI874768; KLC; KLC1; KNS2; KNS2A
UniProt ID: (Human) Q07866, (Rat) P37285
Entrez Gene ID: (Human) 3831, (Mouse) 16593, (Rat) 171041
retrograde vesicle-mediated transport, Golgi to ER
microtubule-based movement
viral process
antigen processing and presentation of exogenous peptide antigen via MHC class II
stress granule disassembly
intracellular protein transport
axo-dendritic transport
protein localization to synapse
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support