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Product Details
13156-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLF12 Fusion Protein Ag3788 (1-402 aa encoded by BC019680)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MNIHMKRKT IKNINTFENR MLMLDGMPAV RVKTELLESE QGSPNVHNYP DMEAVPLLLN NVKGEPPEDS LSVDHFQTQT EPVDLSINKA RTSPTAVSSS PVSMTASASS PSSTSTSSSS SSRLASSPTV ITSVSSASSS STVLTPGPLV ASASGVGGQQ FLHIIHPVPP SSPMNLQSNK LSHVHRIPVV VQSVPVVYTA VRSPGNVNNT IVVPLLEDGR GHGKAQMDPR GLSPRQSKSD SDDDDLPNVT LDSVNETGST ALSIARAVQE VHPSPVSRVR GNRMNNQKFP CSISPFSIES TRRQRRSESP DSRKRRIHRC DFEGCNKVYT KSSHLKAHRR THTGEKPYKC TWEGCTWKFA RSDELTRHYR KHTGVKPFKC ADCDRSFSRS DHLALHRRRH MLV (1-402 aa encoded by BC019680)
Target Information
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AP-2 repressor; AP-2rep transcription factor; BHLHB24; ID; KLF12 zinc finger transcriptional repressor; Krueppel-like factor 12; Kruppel-like factor 12; Transcriptional repressor AP-2rep
Gene Aliases: AP-2rep; AP2REP; HSPC122; KLF12
UniProt ID: (Human) Q9Y4X4
Entrez Gene ID: (Human) 11278
Molecular Function:
C2H2 zinc finger transcription factor
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
metal ion binding
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