|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 164 of Human KLF17|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31774 targets KLF17 in WB applications and shows reactivity with Human samples.
The PA5-31774 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 164 of Human KLF17.
Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Krueppel-like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zfp393; Zinc finger protein 393; ZNF393
Gene Aliases: KLF17; Zfp393; ZNF393
UniProt ID: (Human) Q5JT82
Entrez Gene ID: (Human) 128209
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