This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: TVPSTEAQAV LPSMAQMLPP QDAHDLGMPP AESQSLLVLG SQDSLVSQPD SQEGPFLPEQ PGPAPQTVEK NSRPQEGTG
Highest antigen sequence identity to the following orthologs: Mouse - 42%, Rat - 46%.
KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Krueppel-like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zfp393; Zinc finger protein 393; ZNF393
Gene Aliases: KLF17; Zfp393; ZNF393
UniProt ID: (Human) Q5JT82
Entrez Gene ID: (Human) 128209