Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 24
KLF2 Antibody (PA5-115479) in IHC (P)
Immunohistochemistry analysis of KLF2 in human colorectal cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115479) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115479
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KLF2(Accession Q9Y5W3), corresponding to amino acid residues L56-P106.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900115
Product Specific Information
Antibody detects endogenous levels of total KLF2.
Target Information
KLF2 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Krueppel-like factor 2; Kruppel-like factor 2 (lung); Kruppel-like factor LKLF; Lung krueppel-like factor; lung Kruppel-like factor; lung Kruppel-like zinc finger transcription factor
Gene Aliases: KLF2; LKLF
UniProt ID: (Human) Q9Y5W3, (Mouse) Q60843, (Rat) Q9ET58
Entrez Gene ID: (Human) 10365, (Mouse) 16598, (Rat) 306330
cell morphogenesis
in utero embryonic development
transcription, DNA-templated
negative regulation of interleukin-6 production
multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter in response to stress
regulation of gene expression, epigenetic
erythrocyte maturation
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein metabolic process
Type I pneumocyte differentiation
cellular response to hydrogen peroxide
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to cycloheximide
cellular response to laminar fluid shear stress
cellular response to peptide
regulation of transcription, DNA-templated
erythrocyte homeostasis
response to laminar fluid shear stress
cellular response to organic cyclic compound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support