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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • KLF3 Antibodies

          Invitrogen

          KLF3 Polyclonal Antibody

          View all (8) KLF3 antibodies

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          Cite KLF3 Polyclonal Antibody

          • Antibody Testing Data (2)
          KLF3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          KLF3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          KLF3 Antibody (PA5-30621) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using KLF3 (Product # PA5-30621) antibody at 1:100 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          KLF3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KLF3 Antibody in Western Blot (WB)

          Product Details

          PA5-30621

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human KLF3. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 20% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2548095

          Product Specific Information

          Recommended positive controls: A549, HCT116.

          Predicted reactivity: Human (99%), Mouse (98%), Rat (99%), Pig (99%), Rhesus Monkey (99%), Bovine (99%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          Krueppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and the coregulators with which they interact. KLF6, also designated Zf9 or CPBP (core promoter-binding protein), and KLF3 are Kruppel-like zinc finger containing transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the collagen I promoter, suggesting KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Basic krueppel-like factor; basic kruppel like factor; basic Kruppel-like factor; CACCC-box-binding protein BKLF; Krueppel-like factor 3; Kruppel-like factor 3 (basic); MGC48279; TEF-2; transcript ch138

          View more View less

          Gene Aliases: BKLF; KLF3

          View more View less

          UniProt ID: (Human) P57682

          View more View less

          Entrez Gene ID: (Human) 51274

          View more View less

          Function(s)
          DNA binding transcription factor activity, sequence-specific DNA binding protein binding metal ion binding C2H2 zinc finger transcription factor
          Process(es)
          transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development cellular response to peptide
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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