Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 6 publications 6 publications |
Immunohistochemistry (IHC) |
- | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | View 1 publication 1 publication |
Miscellaneous PubMed (Misc) |
- | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLF5 Fusion Protein Ag15267 (1-350 aa encoded by BC042131) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.4 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
This antibody detects the 50-60 kDa isoform 1 of KLF5. The antibody can recognize isoform 2 (33 kDa) and isoform 3 (18 kDa) too.
Immunogen sequence: MATRVLSMS ARLGPVPQPP APQDEPVFAQ LKPVLGAANP ARDAALFPGE ELKHAHHRPQ AQPAPAQAPQ PAQPPATGPR LPPEDLVQTR CEMEKYLTPQ LPPVPIIPEH KKYRRDSASV VDQFFTDTEG LPYSINMNVF LPDITHLRTG LYKSQRPCVT HIKTEPVAIF SHQSETTAPP PAPTQALPEF TSIFSSHQTA APEVNNIFIK QELPTPDLHL SVPTQQGHLY QLLNTPDLDM PSSTNQTAAM DTLNVSMSAA MAGLNTHTSA VPQTAVKQFQ GMPPCTYTMP SQFLPQQATY FPPSPPSSEP GSPDRQAEML QNLTPPPSYA ATIASKLAIH NPNLPTTLPV N (1-350 aa encoded by BC042131)
KLF5 is a member of the Kruppel-like factor subfamily of zinc finger proteins. It contains three C2H2-type zinc fingers at the carboxyl-terminus that preferentially bind to cis-DNA elements that are GC rich. KLF5 is a transcription activator that promotes cell proliferation and oncogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: (intestinal Kruppel-like factor; basic transcription element binding protein 2; basic transcription element binding protein BTEB2; Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; colon kruppel-like factor; GC box binding protein 2; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Klf5C isoform; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal); RP11-505F3.5; Transcription factor BTEB2
Gene Aliases: 4930520J07Rik; BTEB2; CKLF; IKLF; KLF5
UniProt ID: (Human) Q13887, (Mouse) Q9JMI2
Entrez Gene ID: (Human) 688, (Rat) 84410, (Mouse) 12224
Molecular Function:
C2H2 zinc finger transcription factor
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