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Proteintech
KLHL21 Polyclonal Antibody
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Product Details
16952-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLHL21 Fusion Protein Ag10582 (240-597 aa encoded by BC034039)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AEPLVARCP PCLRLLREAR DFQAARYDRH DRGPCPRMRP RPSTGLAEIL VLVGGCDQDC DELVTVDCYN PQTGQWRYLA EFPDHLGGGY SIVALGNDIY VTGGSDGSRL YDCVWRYNSS VNEWAEVAPM LKAREYHSSS VLDGLLYVVA ADSTERYDHT TDSWEALQPM TYPMDNCSTT ACRGRLYAIG SLAGKETMVM QCYDPDTDLW SLVDCGQLPP WSFAPKTATL NGLMYFVRDD SAEVDVYNPT RNEWDKIPSM NQVHVGGSLA VLGGKLYVSG GYDNTFELSD VVEAYDPETR AWSVVGRLPE PTFWHGSVSI FRQFMPQTFS GGRGFELDSG SDDMDPGRPR PPRDPDELH (240-597 aa encoded by BC034039)
Target Information
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: kelch-like 21; Kelch-like protein 21; MGC99635; unnamed protein product
Gene Aliases: 1810045K06Rik; D330008A20; KIAA0469; KLHL21; mKIAA0469; RGD1305863
UniProt ID: (Human) Q9UJP4, (Mouse) Q3U410, (Rat) D4A2K4
Entrez Gene ID: (Human) 9903, (Mouse) 242785, (Rat) 313743
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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