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Invitrogen
KNTC1 Polyclonal Antibody
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FIGURE: 1 / 1
KNTC1 Antibody (PA5-88956) in WB
Western blot analysis of KNTC1 in extracts of 293T cells. Samples were incubated with KNTC1 Polyclonal antibody (Product # PA5-88956) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-88956
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
2.70 mg/mL
Amount
270 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: 293T; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, kinetochore, spindle
Immunogen sequence: IDLIDREQGE DCLLLLKSLP PAEAEKTAER VIIWARLALQ EEPDHSKEGK AWRMSVAKTS VDILKILCDI QKDNLQKKDE CEEMLKLFKE VASLQENFEV FLSFEDYSNS SLVADLREQH IKAHEVAQAK HKPGSTPEPI AAEVRSPSME SKLHRQALAL QMSKQELEAE LTLRALKDGN IKTALKKCSD LFKYHCNADT G
Target Information
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ36151; HsROD; KIAA0166; Kinetochore-associated protein 1; Rough deal homolog; Rough Deal homolog, centromere/kinetochore protein; unnamed protein product
Gene Aliases: KIAA0166; KNTC1; ROD
UniProt ID: (Human) P50748
Entrez Gene ID: (Human) 9735, (Rat) 304477
mitotic cell cycle checkpoint
mitotic sister chromatid segregation
mitotic spindle assembly checkpoint
regulation of exit from mitosis
cell division
regulation of attachment of spindle microtubules to kinetochore
protein-containing complex assembly
protein localization to kinetochore involved in kinetochore assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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