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Product Details
PA5-21032
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 15 amino acid peptide near the amino terminus of human KPNA1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11155004
Product Specific Information
A suggested positive control is Hela cell lysate.^M
^M
PA5-21032 can be used with blocking peptide PEP-1146.
Target Information
Recombination activating proteins RAG1 and RAG2 regulate and mediate VJ recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in VJ recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IMA2; Importin alpha 2; importin alpha 5; importin alpha-5; Importin alpha-S1; importin subunit alpha-1; Importin subunit alpha-5; importin-alpha-S1; IPOA 1; IPOA1; karyopherin (importin) alpha 1; Karyopherin A2; karyopherin alpha 1 (importin alpha 5); Karyopherin subunit alpha-1; karyopherin/importin alpha-1; KPNA2; m-importin-alpha-S1; NPI-1; Nucleoprotein interactor 1; RAG cohort 1; RAG cohort protein 2; RCH 1; RCH1; recombination activating gene cohort 2; SRP 1; SRP1 alpha; SRP1-beta
Gene Aliases: AW494490; IPOA5; KPNA1; mSRP1; NPI-1; NPI1; RCH2; SRP1
UniProt ID: (Human) P52294, (Mouse) Q60960
Entrez Gene ID: (Human) 3836, (Mouse) 16646, (Rat) 288064
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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