Product References
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers.
Cell chemical biology
Mo X,Tang C,Niu Q,Ma T,Du Y,Fu H
Thu Mar 21 00:00:00 EDT 2019
Zoledronic acid enhances the efficacy of the MEK inhibitor trametinib in KRAS mutant cancers.
Cancer letters
Dai X,Xia H,Zhou S,Tang Q,Bi F
Fri Feb 01 00:00:00 EST 2019
Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells.
Breast cancer research : BCR
Gao P,Wang X,Jin Y,Hu W,Duan Y,Shi A,Du Y,Song D,Yang M,Li S,Han B,Zhao G,Zhang H,Fan Z,Miao QR
Wed Sep 12 00:00:00 EDT 2018
Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.
International journal of oncology
Du Z,Song X,Yan F,Wang J,Zhao Y,Liu S
Tue May 01 00:00:00 EDT 2018
Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.
International journal of oncology
Du Z,Song X,Yan F,Wang J,Zhao Y,Liu S
Tue May 01 00:00:00 EDT 2018
Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.
Cancer science
Akao Y,Kumazaki M,Shinohara H,Sugito N,Kuranaga Y,Tsujino T,Yoshikawa Y,Kitade Y
Tue May 01 00:00:00 EDT 2018
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Cancer letters
Wu D,Zhao B,Qi X,Peng F,Fu H,Chi X,Miao QR,Shao S
Sun Apr 01 00:00:00 EDT 2018
Overexpression of miR-19a inhibits colorectal cancer angiogenesis by suppressing KRAS expression.
Oncology reports
Chen M,Lin M,Wang X
Thu Feb 01 00:00:00 EST 2018
The transcription factor HOXB7 regulates ERK kinase activity and thereby stimulates the motility and invasiveness of pancreatic cancer cells.
The Journal of biological chemistry
Tsuboi M,Taniuchi K,Shimizu T,Saito M,Saibara T
Fri Oct 27 00:00:00 EDT 2017
Lin28B facilitates the progression and metastasis of pancreatic ductal adenocarcinoma.
Oncotarget
Wang Y,Li J,Guo S,Ouyang Y,Yin L,Liu S,Zhao Z,Yang J,Huang W,Qin H,Zhao X,Ni B,Wang H
Fri Sep 01 00:00:00 EDT 2017
A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism.
International journal of oncology
Liu W,Zhang B,Hu Q,Qin Y,Xu W,Shi S,Liang C,Meng Q,Xiang J,Liang D,Ji S,Liu J,Hu P,Liu L,Liu C,Long J,Ni Q,Yu X,Xu J
Mon May 01 00:00:00 EDT 2017
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
Cancer letters
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Yu X,Xu J
Wed Mar 01 00:00:00 EST 2017
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Journal of hematology & oncology
Huang YJ,Yang CK,Wei PL,Huynh TT,Whang-Peng J,Meng TC,Hsiao M,Tzeng YM,Wu AT,Yen Y
Tue Feb 28 00:00:00 EST 2017
Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Molecular cancer research : MCR
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Xu J,Yu X
Wed Feb 01 00:00:00 EST 2017
Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Molecular cancer research : MCR
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Xu J,Yu X
Wed Feb 01 00:00:00 EST 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
Low-Dose Farnesyltransferase Inhibitor Suppresses HIF-1α and Snail Expression in Triple-Negative Breast Cancer MDA-MB-231 Cells In Vitro.
Journal of cellular physiology
Tanaka T,Ikegami Y,Nakazawa H,Kuriyama N,Oki M,Hanai J,Sukhatme VP,Kaneki M
Sun Jan 01 00:00:00 EST 2017
MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42.
Oncotarget
Wang YX,Chen YR,Liu SS,Ye YP,Jiao HL,Wang SY,Xiao ZY,Wei WT,Qiu JF,Liang L,Liao WT,Ding YQ
Tue Dec 20 00:00:00 EST 2016
miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression.
Oncotarget
Ye YP,Wu P,Gu CC,Deng DL,Jiao HL,Li TT,Wang SY,Wang YX,Xiao ZY,Wei WT,Chen YR,Qiu JF,Yang RW,Lin J,Liang L,Liao WT,Ding YQ
Tue Sep 20 00:00:00 EDT 2016
Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells.
Oncogene
Chu PC,Yang MC,Kulp SK,Salunke SB,Himmel LE,Fang CS,Jadhav AM,Shan YS,Lee CT,Lai MD,Shirley LA,Bekaii-Saab T,Chen CS
Thu Jul 28 00:00:00 EDT 2016
Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells.
Oncogene
Chu PC,Yang MC,Kulp SK,Salunke SB,Himmel LE,Fang CS,Jadhav AM,Shan YS,Lee CT,Lai MD,Shirley LA,Bekaii-Saab T,Chen CS
Thu Jul 28 00:00:00 EDT 2016
Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles.
Cancer discovery
Kim E,Ilic N,Shrestha Y,Zou L,Kamburov A,Zhu C,Yang X,Lubonja R,Tran N,Nguyen C,Lawrence MS,Piccioni F,Bagul M,Doench JG,Chouinard CR,Wu X,Hogstrom L,Natoli T,Tamayo P,Horn H,Corsello SM,Lage K,Root DE,Subramanian A,Golub TR,Getz G,Boehm JS,Hahn WC
Fri Jul 01 00:00:00 EDT 2016
Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206.
Oncotarget
Wang SH,Zhang WJ,Wu XC,Zhang MD,Weng MZ,Zhou D,Wang JD,Quan ZW
Tue Jun 21 00:00:00 EDT 2016
Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206.
Oncotarget
Wang SH,Zhang WJ,Wu XC,Zhang MD,Weng MZ,Zhou D,Wang JD,Quan ZW
Tue Jun 21 00:00:00 EDT 2016
Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
Molecular carcinogenesis
Liu W,Ning R,Chen RN,Huang XF,Dai QS,Hu JH,Wang YW,Wu LL,Xiong J,Hu G,Guo QL,Yang J,Wang H
Sun May 01 00:00:00 EDT 2016
Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease.
Oncotarget
Ramraj SK,Aravindan S,Somasundaram DB,Herman TS,Natarajan M,Aravindan N
Tue Apr 05 00:00:00 EDT 2016
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Gene
Xu Q,Fu R,Yin G,Liu X,Liu Y,Xiang M
Thu Mar 10 00:00:00 EST 2016
EGFR phosphorylates FAM129B to promote Ras activation.
Proceedings of the National Academy of Sciences of the United States of America
Ji H,Lee JH,Wang Y,Pang Y,Zhang T,Xia Y,Zhong L,Lyu J,Lu Z
Tue Jan 19 00:00:00 EST 2016
Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats.
The Journal of surgical research
Cao H,Hu X,Zhang Q,Wang J,Li J,Liu B,Shao Y,Li X,Zhang J,Xin S
Sat Nov 01 00:00:00 EDT 2014
Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats.
The Journal of surgical research
Cao H,Hu X,Zhang Q,Wang J,Li J,Liu B,Shao Y,Li X,Zhang J,Xin S
Sat Nov 01 00:00:00 EDT 2014
Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model.
Disease models & mechanisms
Benamrouz S,Conseil V,Chabé M,Praet M,Audebert C,Blervaque R,Guyot K,Gazzola S,Mouray A,Chassat T,Delaire B,Goetinck N,Gantois N,Osman M,Slomianny C,Dehennaut V,Lefebvre T,Viscogliosi E,Cuvelier C,Dei-Cas E,Creusy C,Certad G
Sun Jun 01 00:00:00 EDT 2014
MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2.
The Journal of pathology
Liao WT,Ye YP,Zhang NJ,Li TT,Wang SY,Cui YM,Qi L,Wu P,Jiao HL,Xie YJ,Zhang C,Wang JX,Ding YQ
Sat Mar 01 00:00:00 EST 2014
Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae.
PloS one
Aravindan S,Delma CR,Thirugnanasambandan SS,Herman TS,Aravindan N
Thu Nov 14 00:00:00 EST 2013
Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer.
Investigational new drugs
Laheru D,Shah P,Rajeshkumar NV,McAllister F,Taylor G,Goldsweig H,Le DT,Donehower R,Jimeno A,Linden S,Zhao M,Song D,Rudek MA,Hidalgo M
Sat Dec 01 00:00:00 EST 2012
Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of sp1 to inhibit lung cancer growth.
Molecular pharmacology
Hsu TI,Wang MC,Chen SY,Huang ST,Yeh YM,Su WC,Chang WC,Hung JJ
Sat Dec 01 00:00:00 EST 2012
Investigation of elemene-induced reversal of tamoxifen resistance in MCF-7 cells through oestrogen receptor α (ERα) re-expression.
Breast cancer research and treatment
Zhang B,Zhang X,Tang B,Zheng P,Zhang Y
Thu Nov 01 00:00:00 EDT 2012
Sp1 expression regulates lung tumor progression.
Oncogene
Hsu TI,Wang MC,Chen SY,Yeh YM,Su WC,Chang WC,Hung JJ
Thu Aug 30 00:00:00 EDT 2012
Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer.
The Journal of pathology
Han HB,Gu J,Zuo HJ,Chen ZG,Zhao W,Li M,Ji DB,Lu YY,Zhang ZQ
Wed Feb 01 00:00:00 EST 2012
Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer.
The Journal of pathology
Han HB,Gu J,Zuo HJ,Chen ZG,Zhao W,Li M,Ji DB,Lu YY,Zhang ZQ
Wed Feb 01 00:00:00 EST 2012
Characterization of KRAS rearrangements in metastatic prostate cancer.
Cancer discovery
Wang XS,Shankar S,Dhanasekaran SM,Ateeq B,Sasaki AT,Jing X,Robinson D,Cao Q,Prensner JR,Yocum AK,Wang R,Fries DF,Han B,Asangani IA,Cao X,Li Y,Omenn GS,Pflueger D,Gopalan A,Reuter VE,Kahoud ER,Cantley LC,Rubin MA,Palanisamy N,Varambally S,Chinnaiyan AM
Wed Jun 01 00:00:00 EDT 2011
Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.
Science signaling
Sasaki AT,Carracedo A,Locasale JW,Anastasiou D,Takeuchi K,Kahoud ER,Haviv S,Asara JM,Pandolfi PP,Cantley LC
Tue Mar 08 00:00:00 EST 2011