Product References
Promoted Skin Wound Healing by Tail-Amputated Eisenia foetida Proteins via the Ras/Raf/MEK/ERK Signaling Pathway.
ACS omega
Li T,Sun Y,Wang J,Zhang C,Sun Y
Tue Apr 18 00:00:00 EDT 2023
Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway.
Cell reports
Kim YE,Kim YS,Lee HE,So KH,Choe Y,Suh BC,Kim JH,Park SK,Mathern GW,Gleeson JG,Rah JC,Baek ST
Tue Jan 31 00:00:00 EST 2023
Epitranscriptic regulation of HRAS by N6-methyladenosine drives tumor progression.
Proceedings of the National Academy of Sciences of the United States of America
Pan Y,Gu Y,Liu T,Zhang Q,Yang F,Duan L,Cheng S,Zhu X,Xi Y,Chang X,Ye Q,Gao S
Tue Apr 04 00:00:00 EDT 2023
Gold Nanoparticles Inhibit Macropinocytosis by Decreasing KRAS Activation.
ACS nano
Elechalawar CK,Rao G,Gulla SK,Patel MM,Frickenstein A,Means N,Roy RV,Tsiokas L,Asfa S,Panja P,Rao C,Wilhelm S,Bhattacharya R,Mukherjee P
Tue May 23 00:00:00 EDT 2023
RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.
The Journal of clinical investigation
Ren JG,Xing B,Lv K,O'Keefe RA,Wu M,Wang R,Bauer KM,Ghazaryan A,Burslem GM,Zhang J,O'Connell RM,Pillai V,Hexner EO,Philips MR,Tong W
Thu Jun 15 00:00:00 EDT 2023
The miR-143/145 cluster induced by TGF-β1 suppresses Wilms' tumor 1 expression in cultured human podocytes.
American journal of physiology. Renal physiology
Tabei A,Sakairi T,Hamatani H,Ohishi Y,Watanabe M,Nakasatomi M,Ikeuchi H,Kaneko Y,Kopp JB,Hiromura K
Sat Jul 01 00:00:00 EDT 2023
Intestinal transit amplifying cells require METTL3 for growth factor signaling, KRAS expression, and cell survival.
bioRxiv : the preprint server for biology
Danan CH,Naughton KE,Hayer KE,Vellapan S,McMillan EA,Zhou Y,Matsuda R,Nettleford SK,Katada K,Parham LR,Ma X,Chowdhury A,Wilkins BJ,Shah P,Weitzman MD,Hamilton KE
Fri Apr 21 00:00:00 EDT 2023
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
ACS nano
Zhao C,Liu Z,Chang CC,Chen YC,Zhang Q,Zhang XD,Andreou C,Pang J,Liu ZX,Wang DY,Kircher MF,Yang J
Tue Mar 14 00:00:00 EDT 2023
An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.
Life science alliance
Si Z,Yang G,Wang X,Yu Z,Pang Q,Zhang S,Qian L,Ruan Y,Huang J,Yu L
Wed Mar 01 00:00:00 EST 2023
A TEAD2-Driven Endothelial-Like Program Shapes Basal-Like Differentiation and Metastasis of Pancreatic Cancer.
Gastroenterology
Yoo HB,Moon JW,Kim HR,Lee HS,Miyabayashi K,Park CH,Ge S,Zhang A,Tae YK,Sub Y,Park HW,Gee HY,Notta F,Tuveson DA,Bang S,Kim MY,Roe JS
Sat Jul 01 00:00:00 EDT 2023
A proteomic signature and potential pharmacological opportunities in the adaptive resistance to MEK and PI3K kinase inhibition in pancreatic cancer cells.
Proteomics
Aguilar-Valdés A,González-Vela F,Sánchez-Vidal H,Martínez-Aguilar J
Tue Aug 01 00:00:00 EDT 2023
LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL.
Cancer discovery
Ko A,Hasanain M,Oh YT,D'Angelo F,Sommer D,Frangaj B,Tran S,Bielle F,Pollo B,Paterra R,Mokhtari K,Soni RK,Peyre M,Eoli M,Papi L,Kalamarides M,Sanson M,Iavarone A,Lasorella A
Wed Mar 01 00:00:00 EST 2023
Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence.
Drug design, development and therapy
Liu D,Lin S,Li Y,Zhou T,Hu K,Li Q
Mon Apr 04 00:00:00 EDT 2022
New mechanistic insights into the RAS-SIN1 interaction at the membrane.
Frontiers in cell and developmental biology
Pudewell S,Lissy J,Nakhaeizadeh H,Mosaddeghzadeh N,Nakhaei-Rad S,Dvorsky R,Ahmadian MR
Tue Oct 25 00:00:00 EDT 2022
Oncogenic Kras-Mediated Cytokine CCL15 Regulates Pancreatic Cancer Cell Migration and Invasion through ROS.
Cancers
Messex JK,Adams KLA,Hawkins WG,DeNardo D,Bardeesy N,Billadeau DD,Liou GY
Tue Apr 26 00:00:00 EDT 2022
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Molecular pharmaceutics
Yang X,Shang P,Ji J,Malichewe C,Yao Z,Liao J,Du D,Sun C,Wang L,Tang YJ,Guo X
Mon Jan 03 00:00:00 EST 2022
Mycoplasma gallisepticum induced exosomal gga-miR-193a to disturb cell proliferation, apoptosis, and cytokine production by targeting the KRAS/ERK signaling pathway.
International immunopharmacology
Zou M,Fu Y,Zhao Y,Sun Y,Yin X,Peng X
Sat Oct 01 00:00:00 EDT 2022
Regulation of GTPase function by autophosphorylation.
Molecular cell
Johnson CW,Seo HS,Terrell EM,Yang MH,KleinJan F,Gebregiworgis T,Gasmi-Seabrook GMC,Geffken EA,Lakhani J,Song K,Bashyal P,Popow O,Paulo JA,Liu A,Mattos C,Marshall CB,Ikura M,Morrison DK,Dhe-Paganon S,Haigis KM
Thu Mar 03 00:00:00 EST 2022
Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors.
Nature biotechnology
Davies CW,Oh AJ,Mroue R,Steffek M,Bruning JM,Xiao Y,Feng S,Jayakar S,Chan E,Arumugam V,Uribe SC,Drummond J,Frommlet A,Lu C,Franke Y,Merchant M,Koeppen H,Quinn JG,Malhotra S,Do S,Gazzard L,Purkey HE,Rudolph J,Mulvihill MM,Koerber JT,Wang W,Evangelista M
Sun May 01 00:00:00 EDT 2022
Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes.
Analytical chemistry
Chu H,Zhao Q,Liu J,Yang K,Wang Y,Liu J,Zhang K,Zhao B,He H,Zheng Y,Zhong S,Liang Z,Zhang L,Zhang Y
Tue Jan 18 00:00:00 EST 2022
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone provokes progression from chronic pancreatitis to pancreatic intraepithelial neoplasia.
iScience
Chen X,Sheng L,Ma J,Qi D,Li X,Wang Z,Wu Z,Wong L,Huang JH,Wu E,Ma Q,Zhang D
Fri Jan 21 00:00:00 EST 2022
Identification of MYEOV-Associated Gene Network as a Potential Therapeutic Target in Pancreatic Cancer.
Cancers
Chen Y,Wang J,Guo Q,Li X,Zou X
Fri Nov 04 00:00:00 EDT 2022
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
World journal of gastroenterology
Zhang JJ,Cao CX,Wan LL,Zhang W,Liu ZJ,Wang JL,Guo Q,Tang H
Sat May 07 00:00:00 EDT 2022
Natural product manoalide promotes EGFR-TKI sensitivity of lung cancer cells by KRAS-ERK pathway and mitochondrial Ca2+ overload-induced ferroptosis.
Frontiers in pharmacology
Ni Y,Liu J,Zeng L,Yang Y,Liu L,Yao M,Chai L,Zhang L,Li Y,Zhang L,Li W
Thu Feb 02 00:00:00 EST 2023
Ribitol alters multiple metabolic pathways of central carbon metabolism with enhanced glycolysis: A metabolomics and transcriptomics profiling of breast cancer.
PloS one
Tucker JD,Doddapaneni R,Lu PJ,Lu QL
Thu Dec 15 00:00:00 EST 2022
PD-L1/PD-L1 signalling promotes colorectal cancer cell migration ability through RAS/MEK/ERK.
Clinical and experimental pharmacology & physiology
Cao Y,Liang W,Fang L,Liu MK,Zuo J,Peng YL,Shan JJ,Sun RX,Zhao J,Wang J
Thu Dec 01 00:00:00 EST 2022
PD-L1/PD-L1 signalling promotes colorectal cancer cell migration ability through RAS/MEK/ERK.
Clinical and experimental pharmacology & physiology
Cao Y,Liang W,Fang L,Liu MK,Zuo J,Peng YL,Shan JJ,Sun RX,Zhao J,Wang J
Thu Dec 01 00:00:00 EST 2022
Redox-sensitive small GTPase H-Ras in murine astrocytes, an in vitro study.
Redox report : communications in free radical research
Zuchegna C,Porcellini A,Messina S
Thu Dec 01 00:00:00 EST 2022
In vivo self-assembled small RNAs as a new generation of RNAi therapeutics.
Cell research
Fu Z,Zhang X,Zhou X,Ur-Rehman U,Yu M,Liang H,Guo H,Guo X,Kong Y,Su Y,Ye Y,Hu X,Cheng W,Wu J,Wang Y,Gu Y,Lu SF,Wu D,Zen K,Li J,Yan C,Zhang CY,Chen X
Tue Jun 01 00:00:00 EDT 2021
In vivo self-assembled small RNAs as a new generation of RNAi therapeutics.
Cell research
Fu Z,Zhang X,Zhou X,Ur-Rehman U,Yu M,Liang H,Guo H,Guo X,Kong Y,Su Y,Ye Y,Hu X,Cheng W,Wu J,Wang Y,Gu Y,Lu SF,Wu D,Zen K,Li J,Yan C,Zhang CY,Chen X
Tue Jun 01 00:00:00 EDT 2021
Quadruple-editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells.
Cancer science
Wang Z,Kang B,Gao Q,Huang L,Di J,Fan Y,Yu J,Jiang B,Gao F,Wang D,Sun H,Gu Y,Li J,Su X
Wed Sep 01 00:00:00 EDT 2021
YRDC Mediates the Resistance of Lenvatinib in Hepatocarcinoma Cells via Modulating the Translation of KRAS.
Frontiers in pharmacology
Guo J,Zhu P,Ye Z,Wang M,Yang H,Huang S,Shu Y,Zhang W,Zhou H,Li Q
Fri Oct 22 00:00:00 EDT 2021
Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma.
Frontiers in oncology
Zhang T,Zhu X,Sun Q,Qin X,Zhang Z,Feng Y,Yan M,Chen W
Tue Aug 03 00:00:00 EDT 2021
Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma.
Frontiers in oncology
Zhang T,Zhu X,Sun Q,Qin X,Zhang Z,Feng Y,Yan M,Chen W
Tue Aug 03 00:00:00 EDT 2021
PFP@PLGA/Cu12Sb4S13-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Nano convergence
Dong T,Jiang J,Zhang H,Liu H,Zou X,Niu J,Mao Y,Zhu M,Chen X,Li Z,Chen Y,Shi C,Yang X
Mon Oct 04 00:00:00 EDT 2021
Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research
Liu C,Lu H,Wang H,Loo A,Zhang X,Yang G,Kowal C,Delach S,Wang Y,Goldoni S,Hastings WD,Wong K,Gao H,Meyer MJ,Moody SE,LaMarche MJ,Engelman JA,Williams JA,Hammerman PS,Abrams TJ,Mohseni M,Caponigro G,Hao HX
Fri Jan 01 00:00:00 EST 2021
Hsa-miR-557 Inhibits Osteosarcoma Growth Through Targeting KRAS.
Frontiers in genetics
Qiao Z,Li J,Kou H,Chen X,Bao D,Shang G,Chen S,Ji Y,Cheng T,Wang Y,Liu H
Sat Jan 29 00:00:00 EST 2022
A novel circular RNA, circPUS7 promotes cadmium-induced transformation of human bronchial epithelial cells by regulating Kirsten rat sarcoma viral oncogene homolog expression via sponging miR-770.
Metallomics : integrated biometal science
Pan S,Wang Q,Zhang Q,Zhou M,Li L,Zhou X
Sat Jul 24 00:00:00 EDT 2021
Discovery of a New CDK4/6 and PI3K/AKT Multiple Kinase Inhibitor Aminoquinol for the Treatment of Hepatocellular Carcinoma.
Frontiers in pharmacology
Xia ZK,Wang W,Qiu JG,Shi XN,Li HJ,Chen R,Ke KB,Dong C,Zhu Y,Wu SG,Zhang RP,Meng ZR,Zhao H,Gu P,Leung KS,Wong MH,Liu XD,Zhou FM,Zhang JY,Yao YT,Wang SJ,Zhang CY,Qin YR,Lin MC,Jiang BH
Tue Aug 03 00:00:00 EDT 2021
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Journal of Cancer
Zhang B,Zhang Y,Jiang X,Su H,Wang Q,Wudu M,Jiang J,Ren H,Xu Y,Liu Z,Qiu X
Fri Jan 15 00:00:00 EST 2021
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.
Molecular cell
Sun L,Wang W,Han C,Huang W,Sun Y,Fang K,Zeng Z,Yang Q,Pan Q,Chen T,Luo X,Chen Y
Thu Nov 04 00:00:00 EDT 2021
LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient Prognosis.
Cancer management and research
Cen X,Huang Y,Lu Z,Shao W,Zhuo C,Bao C,Feng S,Wei C,Tang X,Cen L,Guo W,Tian X,Tang Q,Huang X
Mon Apr 25 00:00:00 EDT 2022
Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening.
Journal of molecular cell biology
Du Y,Li X,Niu Q,Mo X,Qui M,Ma T,Kuo CJ,Fu H
Sat Aug 01 00:00:00 EDT 2020
Niclosamide inhibits ovarian carcinoma growth by interrupting cellular bioenergetics.
Journal of Cancer
Shangguan F,Liu Y,Ma L,Qu G,Lv Q,An J,Yang S,Lu B,Cao Q
Mon Sep 28 00:00:00 EDT 2020
Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xiong X,Rao G,Roy RV,Zhang Y,Means N,Dey A,Tsaliki M,Saha S,Bhattacharyya S,Dhar Dwivedi SK,Rao CV,McCormick DJ,Dhanasekaran D,Ding K,Gillies E,Zhang M,Yang D,Bhattacharya R,Mukherjee P
Tue Sep 01 00:00:00 EDT 2020
Immunohistochemical assessment of growth factor signaling molecules: MAPK, Akt, and STAT3 pathways in oral epithelial precursor lesions and squamous cell carcinoma.
Odontology
Tashiro K,Oikawa M,Miki Y,Takahashi T,Kumamoto H
Wed Jan 01 00:00:00 EST 2020
CEP164 Deficiency Causes Hyperproliferation of Pancreatic Cancer Cells.
Frontiers in cell and developmental biology
Kobayashi T,Tanaka K,Mashima Y,Shoda A,Tokuda M,Itoh H
Tue Dec 01 00:00:00 EST 2020
Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy.
Nature communications
Ong T,Trivedi N,Wakefield R,Frase S,Solecki DJ
Tue Oct 20 00:00:00 EDT 2020
Design, synthesis, and biological evaluation of novel substituted thiourea derivatives as potential anticancer agents for NSCLC by blocking K-Ras protein-effectors interactions.
Journal of enzyme inhibition and medicinal chemistry
Zhang Y,Meng X,Tang H,Cheng M,Yang F,Xu W
Tue Dec 01 00:00:00 EST 2020
DEK promotes the proliferation and invasion of lung cancers and indicates poor prognosis in lung adenocarcinomas.
Oncology reports
Yang MQ,Bai LL,Lei L,Zheng YW,Wang Z,Li ZH,Liu CC,Huang WJ,Xu HT
Wed Apr 01 00:00:00 EDT 2020
Comparison of anticarcinogenic properties of Viburnum opulus and its active compound p-coumaric acid on human colorectal carcinoma.
Turkish journal of biology = Turk biyoloji dergisi
Karakurt S,AbuŞo¿lu G,Arituluk ZC
Thu Oct 29 00:00:00 EDT 2020
Ribosome profiling analysis identified a KRAS-interacting microprotein that represses oncogenic signaling in hepatocellular carcinoma cells.
Science China. Life sciences
Xu W,Deng B,Lin P,Liu C,Li B,Huang Q,Zhou H,Yang J,Qu L
Wed Apr 01 00:00:00 EDT 2020
Ribosome profiling analysis identified a KRAS-interacting microprotein that represses oncogenic signaling in hepatocellular carcinoma cells.
Science China. Life sciences
Xu W,Deng B,Lin P,Liu C,Li B,Huang Q,Zhou H,Yang J,Qu L
Wed Apr 01 00:00:00 EDT 2020
VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.
International journal of cancer
Chen Y,Liu Z,Wang H,Tang Z,Liu Y,Liang Z,Deng X,Zhao M,Fu Q,Li L,Cai H,Xie W,Fang W
Wed Jan 15 00:00:00 EST 2020
Establishment and Characterization of Immortalized Miniature Pig Pancreatic Cell Lines Expressing Oncogenic K-RasG12D.
International journal of molecular sciences
Yang HJ,Song BS,Sim BW,Jung Y,Chae U,Lee DG,Cha JJ,Baek SJ,Lim KS,Choi WS,Lee HY,Son HC,Park SH,Jeong KJ,Kang P,Baek SH,Koo BS,Kim HN,Jin YB,Park YH,Choo YK,Kim SU
Sat Nov 21 00:00:00 EST 2020
Precise and efficient silencing of mutant KrasG12D by CRISPR-CasRx controls pancreatic cancer progression.
Theranostics
Jiang W,Li H,Liu X,Zhang J,Zhang W,Li T,Liu L,Yu X
Tue Jun 01 00:00:00 EDT 2021
Precise and efficient silencing of mutant KrasG12D by CRISPR-CasRx controls pancreatic cancer progression.
Theranostics
Jiang W,Li H,Liu X,Zhang J,Zhang W,Li T,Liu L,Yu X
Tue Jun 01 00:00:00 EDT 2021
Discovery of Turn-On Fluorescent Probes for Detecting PDEδ Protein in Living Cells and Tumor Slices.
Analytical chemistry
Dong G,Chen L,Zhang J,Liu T,Du L,Sheng C,Li M
Tue Jul 21 00:00:00 EDT 2020
Cell-type specific tumorigenesis with Ras oncogenes in human lung epithelial cells.
Biochemical and biophysical research communications
Kumazaki M,Shimomura I,Kiyono T,Ochiya T,Yamamoto Y
Thu Apr 30 00:00:00 EDT 2020
Zoledronic acid enhances the efficacy of the MEK inhibitor trametinib in KRAS mutant cancers.
Cancer letters
Dai X,Xia H,Zhou S,Tang Q,Bi F
Fri Feb 01 00:00:00 EST 2019
Zoledronic acid enhances the efficacy of the MEK inhibitor trametinib in KRAS mutant cancers.
Cancer letters
Dai X,Xia H,Zhou S,Tang Q,Bi F
Fri Feb 01 00:00:00 EST 2019
RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer.
Cancer cell international
Zhang X,Ma N,Yao W,Li S,Ren Z
Tue Apr 12 00:00:00 EDT 2022
MEK nuclear localization promotes YAP stability via sequestering β-TrCP in KRAS mutant cancer cells.
Cell death and differentiation
Xu H,Zhou S,Xia H,Yu H,Tang Q,Bi F
Fri Nov 01 00:00:00 EDT 2019
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Molecular therapy oncolytics
Zhao H,Wu S,Li H,Duan Q,Zhang Z,Shen Q,Wang C,Yin T
Fri Sep 27 00:00:00 EDT 2019
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Molecular therapy oncolytics
Zhao H,Wu S,Li H,Duan Q,Zhang Z,Shen Q,Wang C,Yin T
Fri Sep 27 00:00:00 EDT 2019
Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma.
Cell death & disease
Huang L,Wang Y,Chen J,Wang Y,Zhao Y,Wang Y,Ma Y,Chen X,Liu W,Li Z,Zhao L,Shan B,Dong X,Li D,Shao S,Song Y,Zhan Q,Liu X
Thu Jul 04 00:00:00 EDT 2019
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.
Nature communications
Sale MJ,Minihane E,Monks NR,Gilley R,Richards FM,Schifferli KP,Andersen CL,Davies EJ,Vicente MA,Ozono E,Markovets A,Dry JR,Drew L,Flemington V,Proia T,Jodrell DI,Smith PD,Cook SJ
Thu Nov 14 00:00:00 EST 2019
Characterization of Protein Profiling and mRNA Expression of LLC Exosomes.
The protein journal
Zhang W,He P,Wang S,Adili A,Chen Z,Zhang CY,Jiang X,Li J,Zhang Y
Tue Oct 01 00:00:00 EDT 2019
Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Chen Z,Yang D,Jiang X,Tian L,Sun J,Tian D,Bai W
Thu Aug 01 00:00:00 EDT 2019
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer.
eLife
Adams CR,Htwe HH,Marsh T,Wang AL,Montoya ML,Subbaraj L,Tward AD,Bardeesy N,Perera RM
Tue May 28 00:00:00 EDT 2019
Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition.
Nature communications
Gao L,Hu Y,Tian Y,Fan Z,Wang K,Li H,Zhou Q,Zeng G,Hu X,Yu L,Zhou S,Tong X,Huang H,Chen H,Liu Q,Liu W,Zhang G,Zeng M,Zhou G,He Q,Ji H,Chen L
Wed Apr 10 00:00:00 EDT 2019
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
Environment international
Chen S,Li D,Zhang H,Yu D,Chen R,Zhang B,Tan Y,Niu Y,Duan H,Mai B,Chen S,Yu J,Luan T,Chen L,Xing X,Li Q,Xiao Y,Dong G,Niu Y,Aschner M,Zhang R,Zheng Y,Chen W
Tue Oct 01 00:00:00 EDT 2019
UBN2 promotes tumor progression via the Ras/MAPK pathway and predicts poor prognosis in colorectal cancer.
Cancer cell international
Zhao YL,Zhong SR,Zhang SH,Bi JX,Xiao ZY,Wang SY,Jiao HL,Zhang D,Qiu JF,Zhang LJ,Huang CM,Chen XL,Ding YQ,Ye YP,Liang L,Liao WT
Fri Apr 08 00:00:00 EDT 2022
Apigenin Combined With Gefitinib Blocks Autophagy Flux and Induces Apoptotic Cell Death Through Inhibition of HIF-1α, c-Myc, p-EGFR, and Glucose Metabolism in EGFR L858R+T790M-Mutated H1975 Cells.
Frontiers in pharmacology
Chen Z,Tian D,Liao X,Zhang Y,Xiao J,Chen W,Liu Q,Chen Y,Li D,Zhu L,Cai S
Wed Sep 30 00:00:00 EDT 2020
KRAS regulation by small non-coding RNAs and SNARE proteins.
Nature communications
Che Y,Siprashvili Z,Kovalski JR,Jiang T,Wozniak G,Elcavage L,Khavari PA
Mon Nov 11 00:00:00 EST 2019
SHIP1 inhibits cell growth, migration, and invasion in non‑small cell lung cancer through the PI3K/AKT pathway.
Oncology reports
Fu Q,Huang Y,Ge C,Li Z,Tian H,Li Q,Li H,Li R,Tao X,Xue Y,Wang Y,Yang G,Fang W,Song X
Mon Apr 01 00:00:00 EDT 2019
Effectiveness of a genetic test panel designed for gynecological cancer: an exploratory study.
Medical oncology (Northwood, London, England)
Ida K,Miyamoto T,Higuchi S,Takeuchi H,Yamada S,Ono M,Nishihara H,Shiozawa T
Wed May 29 00:00:00 EDT 2019
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers.
Cell chemical biology
Mo X,Tang C,Niu Q,Ma T,Du Y,Fu H
Thu Mar 21 00:00:00 EDT 2019
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers.
Cell chemical biology
Mo X,Tang C,Niu Q,Ma T,Du Y,Fu H
Thu Mar 21 00:00:00 EDT 2019
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Cancer letters
Wu D,Zhao B,Qi X,Peng F,Fu H,Chi X,Miao QR,Shao S
Sun Apr 01 00:00:00 EDT 2018
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Cancer letters
Wu D,Zhao B,Qi X,Peng F,Fu H,Chi X,Miao QR,Shao S
Sun Apr 01 00:00:00 EDT 2018
Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells.
Breast cancer research : BCR
Gao P,Wang X,Jin Y,Hu W,Duan Y,Shi A,Du Y,Song D,Yang M,Li S,Han B,Zhao G,Zhang H,Fan Z,Miao QR
Wed Sep 12 00:00:00 EDT 2018
Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells.
Breast cancer research : BCR
Gao P,Wang X,Jin Y,Hu W,Duan Y,Shi A,Du Y,Song D,Yang M,Li S,Han B,Zhao G,Zhang H,Fan Z,Miao QR
Wed Sep 12 00:00:00 EDT 2018
Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.
Cancer science
Akao Y,Kumazaki M,Shinohara H,Sugito N,Kuranaga Y,Tsujino T,Yoshikawa Y,Kitade Y
Tue May 01 00:00:00 EDT 2018
Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.
Cancer science
Akao Y,Kumazaki M,Shinohara H,Sugito N,Kuranaga Y,Tsujino T,Yoshikawa Y,Kitade Y
Tue May 01 00:00:00 EDT 2018
Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.
International journal of oncology
Du Z,Song X,Yan F,Wang J,Zhao Y,Liu S
Tue May 01 00:00:00 EDT 2018
Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.
International journal of oncology
Du Z,Song X,Yan F,Wang J,Zhao Y,Liu S
Tue May 01 00:00:00 EDT 2018
Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.
International journal of oncology
Du Z,Song X,Yan F,Wang J,Zhao Y,Liu S
Tue May 01 00:00:00 EDT 2018
Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.
International journal of oncology
Du Z,Song X,Yan F,Wang J,Zhao Y,Liu S
Tue May 01 00:00:00 EDT 2018
Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.
International journal of oncology
Du Z,Song X,Yan F,Wang J,Zhao Y,Liu S
Tue May 01 00:00:00 EDT 2018
Overexpression of miR-19a inhibits colorectal cancer angiogenesis by suppressing KRAS expression.
Oncology reports
Chen M,Lin M,Wang X
Thu Feb 01 00:00:00 EST 2018
Overexpression of miR-19a inhibits colorectal cancer angiogenesis by suppressing KRAS expression.
Oncology reports
Chen M,Lin M,Wang X
Thu Feb 01 00:00:00 EST 2018
Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Oncogene
Chu PC,Lin PC,Wu HY,Lin KT,Wu C,Bekaii-Saab T,Lin YJ,Lee CT,Lee JC,Chen CS
Fri Jun 01 00:00:00 EDT 2018
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
Cancer letters
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Yu X,Xu J
Wed Mar 01 00:00:00 EST 2017
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
Cancer letters
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Yu X,Xu J
Wed Mar 01 00:00:00 EST 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
Low-Dose Farnesyltransferase Inhibitor Suppresses HIF-1α and Snail Expression in Triple-Negative Breast Cancer MDA-MB-231 Cells In Vitro.
Journal of cellular physiology
Tanaka T,Ikegami Y,Nakazawa H,Kuriyama N,Oki M,Hanai J,Sukhatme VP,Kaneki M
Sun Jan 01 00:00:00 EST 2017
Low-Dose Farnesyltransferase Inhibitor Suppresses HIF-1α and Snail Expression in Triple-Negative Breast Cancer MDA-MB-231 Cells In Vitro.
Journal of cellular physiology
Tanaka T,Ikegami Y,Nakazawa H,Kuriyama N,Oki M,Hanai J,Sukhatme VP,Kaneki M
Sun Jan 01 00:00:00 EST 2017
Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Molecular cancer research : MCR
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Xu J,Yu X
Wed Feb 01 00:00:00 EST 2017
Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Molecular cancer research : MCR
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Xu J,Yu X
Wed Feb 01 00:00:00 EST 2017
Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Molecular cancer research : MCR
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Xu J,Yu X
Wed Feb 01 00:00:00 EST 2017
Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Molecular cancer research : MCR
Liang C,Qin Y,Zhang B,Ji S,Shi S,Xu W,Liu J,Xiang J,Liang D,Hu Q,Ni Q,Xu J,Yu X
Wed Feb 01 00:00:00 EST 2017
A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism.
International journal of oncology
Liu W,Zhang B,Hu Q,Qin Y,Xu W,Shi S,Liang C,Meng Q,Xiang J,Liang D,Ji S,Liu J,Hu P,Liu L,Liu C,Long J,Ni Q,Yu X,Xu J
Mon May 01 00:00:00 EDT 2017
A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism.
International journal of oncology
Liu W,Zhang B,Hu Q,Qin Y,Xu W,Shi S,Liang C,Meng Q,Xiang J,Liang D,Ji S,Liu J,Hu P,Liu L,Liu C,Long J,Ni Q,Yu X,Xu J
Mon May 01 00:00:00 EDT 2017
The transcription factor HOXB7 regulates ERK kinase activity and thereby stimulates the motility and invasiveness of pancreatic cancer cells.
The Journal of biological chemistry
Tsuboi M,Taniuchi K,Shimizu T,Saito M,Saibara T
Fri Oct 27 00:00:00 EDT 2017
The transcription factor HOXB7 regulates ERK kinase activity and thereby stimulates the motility and invasiveness of pancreatic cancer cells.
The Journal of biological chemistry
Tsuboi M,Taniuchi K,Shimizu T,Saito M,Saibara T
Fri Oct 27 00:00:00 EDT 2017
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Journal of hematology & oncology
Huang YJ,Yang CK,Wei PL,Huynh TT,Whang-Peng J,Meng TC,Hsiao M,Tzeng YM,Wu AT,Yen Y
Tue Feb 28 00:00:00 EST 2017
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Journal of hematology & oncology
Huang YJ,Yang CK,Wei PL,Huynh TT,Whang-Peng J,Meng TC,Hsiao M,Tzeng YM,Wu AT,Yen Y
Tue Feb 28 00:00:00 EST 2017
Lin28B facilitates the progression and metastasis of pancreatic ductal adenocarcinoma.
Oncotarget
Wang Y,Li J,Guo S,Ouyang Y,Yin L,Liu S,Zhao Z,Yang J,Huang W,Qin H,Zhao X,Ni B,Wang H
Fri Sep 01 00:00:00 EDT 2017
Lin28B facilitates the progression and metastasis of pancreatic ductal adenocarcinoma.
Oncotarget
Wang Y,Li J,Guo S,Ouyang Y,Yin L,Liu S,Zhao Z,Yang J,Huang W,Qin H,Zhao X,Ni B,Wang H
Fri Sep 01 00:00:00 EDT 2017
Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles.
Cancer discovery
Kim E,Ilic N,Shrestha Y,Zou L,Kamburov A,Zhu C,Yang X,Lubonja R,Tran N,Nguyen C,Lawrence MS,Piccioni F,Bagul M,Doench JG,Chouinard CR,Wu X,Hogstrom L,Natoli T,Tamayo P,Horn H,Corsello SM,Lage K,Root DE,Subramanian A,Golub TR,Getz G,Boehm JS,Hahn WC
Fri Jul 01 00:00:00 EDT 2016
Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles.
Cancer discovery
Kim E,Ilic N,Shrestha Y,Zou L,Kamburov A,Zhu C,Yang X,Lubonja R,Tran N,Nguyen C,Lawrence MS,Piccioni F,Bagul M,Doench JG,Chouinard CR,Wu X,Hogstrom L,Natoli T,Tamayo P,Horn H,Corsello SM,Lage K,Root DE,Subramanian A,Golub TR,Getz G,Boehm JS,Hahn WC
Fri Jul 01 00:00:00 EDT 2016
EGFR phosphorylates FAM129B to promote Ras activation.
Proceedings of the National Academy of Sciences of the United States of America
Ji H,Lee JH,Wang Y,Pang Y,Zhang T,Xia Y,Zhong L,Lyu J,Lu Z
Tue Jan 19 00:00:00 EST 2016
EGFR phosphorylates FAM129B to promote Ras activation.
Proceedings of the National Academy of Sciences of the United States of America
Ji H,Lee JH,Wang Y,Pang Y,Zhang T,Xia Y,Zhong L,Lyu J,Lu Z
Tue Jan 19 00:00:00 EST 2016
Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells.
Oncogene
Chu PC,Yang MC,Kulp SK,Salunke SB,Himmel LE,Fang CS,Jadhav AM,Shan YS,Lee CT,Lai MD,Shirley LA,Bekaii-Saab T,Chen CS
Thu Jul 28 00:00:00 EDT 2016
Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells.
Oncogene
Chu PC,Yang MC,Kulp SK,Salunke SB,Himmel LE,Fang CS,Jadhav AM,Shan YS,Lee CT,Lai MD,Shirley LA,Bekaii-Saab T,Chen CS
Thu Jul 28 00:00:00 EDT 2016
Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells.
Oncogene
Chu PC,Yang MC,Kulp SK,Salunke SB,Himmel LE,Fang CS,Jadhav AM,Shan YS,Lee CT,Lai MD,Shirley LA,Bekaii-Saab T,Chen CS
Thu Jul 28 00:00:00 EDT 2016
Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells.
Oncogene
Chu PC,Yang MC,Kulp SK,Salunke SB,Himmel LE,Fang CS,Jadhav AM,Shan YS,Lee CT,Lai MD,Shirley LA,Bekaii-Saab T,Chen CS
Thu Jul 28 00:00:00 EDT 2016
Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
Molecular carcinogenesis
Liu W,Ning R,Chen RN,Huang XF,Dai QS,Hu JH,Wang YW,Wu LL,Xiong J,Hu G,Guo QL,Yang J,Wang H
Sun May 01 00:00:00 EDT 2016
Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
Molecular carcinogenesis
Liu W,Ning R,Chen RN,Huang XF,Dai QS,Hu JH,Wang YW,Wu LL,Xiong J,Hu G,Guo QL,Yang J,Wang H
Sun May 01 00:00:00 EDT 2016
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Gene
Xu Q,Fu R,Yin G,Liu X,Liu Y,Xiang M
Thu Mar 10 00:00:00 EST 2016
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Gene
Xu Q,Fu R,Yin G,Liu X,Liu Y,Xiang M
Thu Mar 10 00:00:00 EST 2016
MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42.
Oncotarget
Wang YX,Chen YR,Liu SS,Ye YP,Jiao HL,Wang SY,Xiao ZY,Wei WT,Qiu JF,Liang L,Liao WT,Ding YQ
Tue Dec 20 00:00:00 EST 2016
MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42.
Oncotarget
Wang YX,Chen YR,Liu SS,Ye YP,Jiao HL,Wang SY,Xiao ZY,Wei WT,Qiu JF,Liang L,Liao WT,Ding YQ
Tue Dec 20 00:00:00 EST 2016
Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease.
Oncotarget
Ramraj SK,Aravindan S,Somasundaram DB,Herman TS,Natarajan M,Aravindan N
Tue Apr 05 00:00:00 EDT 2016
Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease.
Oncotarget
Ramraj SK,Aravindan S,Somasundaram DB,Herman TS,Natarajan M,Aravindan N
Tue Apr 05 00:00:00 EDT 2016
Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease.
Oncotarget
Ramraj SK,Aravindan S,Somasundaram DB,Herman TS,Natarajan M,Aravindan N
Tue Apr 05 00:00:00 EDT 2016
Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206.
Oncotarget
Wang SH,Zhang WJ,Wu XC,Zhang MD,Weng MZ,Zhou D,Wang JD,Quan ZW
Tue Jun 21 00:00:00 EDT 2016
Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206.
Oncotarget
Wang SH,Zhang WJ,Wu XC,Zhang MD,Weng MZ,Zhou D,Wang JD,Quan ZW
Tue Jun 21 00:00:00 EDT 2016
Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206.
Oncotarget
Wang SH,Zhang WJ,Wu XC,Zhang MD,Weng MZ,Zhou D,Wang JD,Quan ZW
Tue Jun 21 00:00:00 EDT 2016
Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206.
Oncotarget
Wang SH,Zhang WJ,Wu XC,Zhang MD,Weng MZ,Zhou D,Wang JD,Quan ZW
Tue Jun 21 00:00:00 EDT 2016
SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status.
Oncotarget
Song HY,Biancucci M,Kang HJ,O'Callaghan C,Park SH,Principe DR,Jiang H,Yan Y,Satchell KF,Raparia K,Gius D,Vassilopoulos A
Tue Dec 06 00:00:00 EST 2016
miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression.
Oncotarget
Ye YP,Wu P,Gu CC,Deng DL,Jiao HL,Li TT,Wang SY,Wang YX,Xiao ZY,Wei WT,Chen YR,Qiu JF,Yang RW,Lin J,Liang L,Liao WT,Ding YQ
Tue Sep 20 00:00:00 EDT 2016
miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression.
Oncotarget
Ye YP,Wu P,Gu CC,Deng DL,Jiao HL,Li TT,Wang SY,Wang YX,Xiao ZY,Wei WT,Chen YR,Qiu JF,Yang RW,Lin J,Liang L,Liao WT,Ding YQ
Tue Sep 20 00:00:00 EDT 2016
Expression of KRAS in the endometrium of early pregnant mice and its effect during embryo implantation.
Reproductive biomedicine online
Long X,Zhang M,Chen X,He J,Ding Y,Zhang C,Liu X,Wang Y
Wed Jul 01 00:00:00 EDT 2015
Expression of KRAS in the endometrium of early pregnant mice and its effect during embryo implantation.
Reproductive biomedicine online
Long X,Zhang M,Chen X,He J,Ding Y,Zhang C,Liu X,Wang Y
Wed Jul 01 00:00:00 EDT 2015
MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2.
The Journal of pathology
Liao WT,Ye YP,Zhang NJ,Li TT,Wang SY,Cui YM,Qi L,Wu P,Jiao HL,Xie YJ,Zhang C,Wang JX,Ding YQ
Sat Mar 01 00:00:00 EST 2014
MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2.
The Journal of pathology
Liao WT,Ye YP,Zhang NJ,Li TT,Wang SY,Cui YM,Qi L,Wu P,Jiao HL,Xie YJ,Zhang C,Wang JX,Ding YQ
Sat Mar 01 00:00:00 EST 2014
Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model.
Disease models & mechanisms
Benamrouz S,Conseil V,Chabé M,Praet M,Audebert C,Blervaque R,Guyot K,Gazzola S,Mouray A,Chassat T,Delaire B,Goetinck N,Gantois N,Osman M,Slomianny C,Dehennaut V,Lefebvre T,Viscogliosi E,Cuvelier C,Dei-Cas E,Creusy C,Certad G
Sun Jun 01 00:00:00 EDT 2014
Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model.
Disease models & mechanisms
Benamrouz S,Conseil V,Chabé M,Praet M,Audebert C,Blervaque R,Guyot K,Gazzola S,Mouray A,Chassat T,Delaire B,Goetinck N,Gantois N,Osman M,Slomianny C,Dehennaut V,Lefebvre T,Viscogliosi E,Cuvelier C,Dei-Cas E,Creusy C,Certad G
Sun Jun 01 00:00:00 EDT 2014
Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats.
The Journal of surgical research
Cao H,Hu X,Zhang Q,Wang J,Li J,Liu B,Shao Y,Li X,Zhang J,Xin S
Sat Nov 01 00:00:00 EDT 2014
Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats.
The Journal of surgical research
Cao H,Hu X,Zhang Q,Wang J,Li J,Liu B,Shao Y,Li X,Zhang J,Xin S
Sat Nov 01 00:00:00 EDT 2014
Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats.
The Journal of surgical research
Cao H,Hu X,Zhang Q,Wang J,Li J,Liu B,Shao Y,Li X,Zhang J,Xin S
Sat Nov 01 00:00:00 EDT 2014
Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats.
The Journal of surgical research
Cao H,Hu X,Zhang Q,Wang J,Li J,Liu B,Shao Y,Li X,Zhang J,Xin S
Sat Nov 01 00:00:00 EDT 2014
Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae.
PloS one
Aravindan S,Delma CR,Thirugnanasambandan SS,Herman TS,Aravindan N
Thu Nov 14 00:00:00 EST 2013
Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae.
PloS one
Aravindan S,Delma CR,Thirugnanasambandan SS,Herman TS,Aravindan N
Thu Nov 14 00:00:00 EST 2013
Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer.
The Journal of pathology
Han HB,Gu J,Zuo HJ,Chen ZG,Zhao W,Li M,Ji DB,Lu YY,Zhang ZQ
Wed Feb 01 00:00:00 EST 2012
Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer.
The Journal of pathology
Han HB,Gu J,Zuo HJ,Chen ZG,Zhao W,Li M,Ji DB,Lu YY,Zhang ZQ
Wed Feb 01 00:00:00 EST 2012
Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer.
The Journal of pathology
Han HB,Gu J,Zuo HJ,Chen ZG,Zhao W,Li M,Ji DB,Lu YY,Zhang ZQ
Wed Feb 01 00:00:00 EST 2012
Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer.
The Journal of pathology
Han HB,Gu J,Zuo HJ,Chen ZG,Zhao W,Li M,Ji DB,Lu YY,Zhang ZQ
Wed Feb 01 00:00:00 EST 2012
Sp1 expression regulates lung tumor progression.
Oncogene
Hsu TI,Wang MC,Chen SY,Yeh YM,Su WC,Chang WC,Hung JJ
Thu Aug 30 00:00:00 EDT 2012
Sp1 expression regulates lung tumor progression.
Oncogene
Hsu TI,Wang MC,Chen SY,Yeh YM,Su WC,Chang WC,Hung JJ
Thu Aug 30 00:00:00 EDT 2012
Investigation of elemene-induced reversal of tamoxifen resistance in MCF-7 cells through oestrogen receptor α (ERα) re-expression.
Breast cancer research and treatment
Zhang B,Zhang X,Tang B,Zheng P,Zhang Y
Thu Nov 01 00:00:00 EDT 2012
Investigation of elemene-induced reversal of tamoxifen resistance in MCF-7 cells through oestrogen receptor α (ERα) re-expression.
Breast cancer research and treatment
Zhang B,Zhang X,Tang B,Zheng P,Zhang Y
Thu Nov 01 00:00:00 EDT 2012
Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of sp1 to inhibit lung cancer growth.
Molecular pharmacology
Hsu TI,Wang MC,Chen SY,Huang ST,Yeh YM,Su WC,Chang WC,Hung JJ
Sat Dec 01 00:00:00 EST 2012
Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of sp1 to inhibit lung cancer growth.
Molecular pharmacology
Hsu TI,Wang MC,Chen SY,Huang ST,Yeh YM,Su WC,Chang WC,Hung JJ
Sat Dec 01 00:00:00 EST 2012
Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer.
Investigational new drugs
Laheru D,Shah P,Rajeshkumar NV,McAllister F,Taylor G,Goldsweig H,Le DT,Donehower R,Jimeno A,Linden S,Zhao M,Song D,Rudek MA,Hidalgo M
Sat Dec 01 00:00:00 EST 2012
Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer.
Investigational new drugs
Laheru D,Shah P,Rajeshkumar NV,McAllister F,Taylor G,Goldsweig H,Le DT,Donehower R,Jimeno A,Linden S,Zhao M,Song D,Rudek MA,Hidalgo M
Sat Dec 01 00:00:00 EST 2012
Characterization of KRAS rearrangements in metastatic prostate cancer.
Cancer discovery
Wang XS,Shankar S,Dhanasekaran SM,Ateeq B,Sasaki AT,Jing X,Robinson D,Cao Q,Prensner JR,Yocum AK,Wang R,Fries DF,Han B,Asangani IA,Cao X,Li Y,Omenn GS,Pflueger D,Gopalan A,Reuter VE,Kahoud ER,Cantley LC,Rubin MA,Palanisamy N,Varambally S,Chinnaiyan AM
Wed Jun 01 00:00:00 EDT 2011
Characterization of KRAS rearrangements in metastatic prostate cancer.
Cancer discovery
Wang XS,Shankar S,Dhanasekaran SM,Ateeq B,Sasaki AT,Jing X,Robinson D,Cao Q,Prensner JR,Yocum AK,Wang R,Fries DF,Han B,Asangani IA,Cao X,Li Y,Omenn GS,Pflueger D,Gopalan A,Reuter VE,Kahoud ER,Cantley LC,Rubin MA,Palanisamy N,Varambally S,Chinnaiyan AM
Wed Jun 01 00:00:00 EDT 2011
Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.
Science signaling
Sasaki AT,Carracedo A,Locasale JW,Anastasiou D,Takeuchi K,Kahoud ER,Haviv S,Asara JM,Pandolfi PP,Cantley LC
Tue Mar 08 00:00:00 EST 2011
Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.
Science signaling
Sasaki AT,Carracedo A,Locasale JW,Anastasiou D,Takeuchi K,Kahoud ER,Haviv S,Asara JM,Pandolfi PP,Cantley LC
Tue Mar 08 00:00:00 EST 2011
small GTPase
