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Invitrogen
KRT16 Polyclonal Antibody
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Product Details
PA5-109897
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
2.97 mg/mL
Amount
297 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LQIDNARLAA DDFRTKYEHE LALRQTVEAD VNGLRRVLDE LTLARTDLEM QIEGLKEELA YLRKNHEEEM LALRGQTGGD VNVEMDAAPG VDLSRILNEM RDQYEQMAEK NRRDAETWFL SKTEELNKEV ASNSELVQSS RSEVTELRRV LQGLEIELQS QLSMKASLEN SLEETKGRYC MQLSQIQGLI GSVEEQLAQL RCEMEQQSQE YQILLDVKTR LEQEIATYRR LLEGEDAHLS S
Target Information
KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-16; cytokeratin 16; Cytokeratin-16; focal non-epidermolytic palmoplantar keratoderma; intermediate filament protein K16; K16; keratin 16 homolog; keratin 16, type I; keratin complex 1, acidic, gene 16; keratin intermediate filament 16a; keratin intermediate filament 16b; Keratin, type I cytoskeletal 16; Keratin-16; type I keratin KA16; unnamed protein product
Gene Aliases: AI324768; CK16; FNEPPK; K16; K1CP; Ka16; Krt1-16; KRT16; KRT16A; NEPPK; PC1
UniProt ID: (Human) P08779, (Mouse) Q9Z2K1
Entrez Gene ID: (Human) 3868, (Mouse) 16666, (Rat) 303530
morphogenesis of an epithelium
immune system process
inflammatory response
aging
keratinocyte differentiation
negative regulation of cell migration
keratinization
hair cycle
innate immune response
intermediate filament cytoskeleton organization
keratinocyte migration
establishment of skin barrier
cytoskeleton organization
intermediate filament organization
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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