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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RWHLGPGDPFSTYV) corresponding to the C-terminus amino acids of KALRN|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||Assay dependent|
|Western Blot (WB)||0.1-0.3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Huntington's disease , a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cyclin B1; DUET; DUO; FLJ12332; FLJ16443; FLJ18196; FLJ18623; HAPIP; hCG_2022551; huntingtin-associated protein interacting protein (duo); huntingtin-associated protein-interacting protein; kalirin; kalirin, RhoGEF kinase; KALRN; P-CIP10; PAM COOH-terminal interactor protein 10; protein Duo; serine/threonine kinase with Dbl- and pleckstrin homology domain; serine/threonine kinase with Dbl- and pleckstrin homology domains; serine/threonine-protein kinase with Dbl- and pleckstrin homology domain
2210407G14Rik; ARHGEF24; AV235988; CHD5; CHDS5; DUET; DUO; E530005C20Rik; Gm539; HAPIP; Kalirin; KALRN; TRAD