Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji , mouse brain.
Predicted reactivity: Mouse (81%), Rat (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hippostasin; hK11; kallikrein 11; Kallikrein-11; kallikrein-related peptidase 11; Kallikrein11; protease, serine, 20; Serine protease 20; Trypsin-like protease
Gene Aliases: 2310015I08Rik; KLK11; PRSS20; TLSP; UNQ649/PRO1279
UniProt ID: (Human) Q9UBX7, (Mouse) Q9QYN3
Entrez Gene ID: (Human) 11012, (Mouse) 56538
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