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Proteintech
Kv4.1 Polyclonal Antibody
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Product Details
13768-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Kv4.1 Fusion Protein Ag4751 (410-647 aa encoded by BC045659)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NFSRIYHQN QRADKRRAQQ KVRLARIRLA KSGTTNAFLQ YKQNGGLEDS GSGEEQALCV RNRSAFEQQH HHLLHCLEKT TCHEFTDELT FSEALGAVSP GGRTSRSTSV SSQPVGPGSL LSSCCPRRAK RRAIRLANST ASVSRGSMQE LDMLAGLRRS HAPQSRSSLN AKPHDSLDLN CDSRDFVAAI ISIPTPPANT PDESQPSSPG GGGRAGSTLR NSSLGTPCLF PETVKISSL (410-647 aa encoded by BC045659)
Target Information
The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1. 1, KV1. 2 and KV1. 4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A-type voltage-gated potassium channel KCND1; mShal; potassium channel, voltage gated Shal related subfamily D, member 1; potassium voltage gated channel Shal-related family member 1; potassium voltage gated channel, Shal-related family, member 1; Potassium voltage-gated channel subfamily D member 1; potassium voltage-gated channel, Shal-related family, member 1; potassium voltage-gated channel, Shal-related subfamily, member 1; Shal-type potassium channel; Shal-type potassium channel KCND1; Voltage-gated potassium channel subunit Kv4.1
Gene Aliases: 1110037K09Rik; Kca2-1; KCND1; KV4.1; mShal1; Shal; Shal1
UniProt ID: (Human) Q9NSA2, (Mouse) Q03719
Entrez Gene ID: (Human) 3750, (Mouse) 16506, (Rat) 116695
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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