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Invitrogen
L-Ficolin Polyclonal Antibody
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Product Details
PA5149925
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Ficolin 2 (FCN2) (Gln97-Ser254)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collagen/fibrinogen domain-containing protein 2; Ficolin-2; Ficolin-B; Ficolin-beta; L-ficolin; RP11-263F14.2
Gene Aliases: Fcn2; Fcnb
UniProt ID: (Mouse) O70497
Entrez Gene ID: (Mouse) 14134
complement activation, lectin pathway
immune system process
cell surface pattern recognition receptor signaling pathway
G-protein coupled receptor signaling pathway
protein localization to cell surface
recognition of apoptotic cell
innate immune response
negative regulation of viral entry into host cell
positive regulation of interleukin-8 secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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